Entrepreneurism in Medical Device Development An Evolutionary Path
, 2017 The 2017 Translational Medicine Symposium was held on Feb. 27th. The symposium addressed how clinicians\u27 ideas and research results can have an impact on patient care - if they are translated into clinical practice.
Derek Sakata, MD
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Translational medicine at the Kazan Federal University
Учёные записки Казанского университета: Серия Естественные науки, 2017 The world has changed considerably after the latest technological revolutions, such the genomic and fourth industrial ones. This has been paralleled by an increasing awareness of the importance of transformations in the sphere of higher education.
А.P. Kiassov +5 more
doaj
BENCH TO BEDSIDE: CHALLENGES AND OPPORTUNITIES IN LOW- AND MIDDLE-INCOME COUNTRIES
Liaquat Medical Research JournalTranslational research is a modern era of medical and clinical research where basic research discoveries are brought in the clinical practice to the patient care.
Binafsha Manzoor Syed
doaj +1 more source
100 Integration of the Group of Student Leaders to the Title V Medical Sciences Campus (MSC) Project from the University of Puerto Rico (UPR) to collaborate in increasing the number of undergraduate (UgS) and graduate students (GS) from Puerto Rico with the knowledge, skills, abilities and opportunities in Clinical and Translational Research (CTR) [PDF]
, 2023 Juan C Soto-Santiago +4 more
openalex +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Greater gulf coast regional translational workforce development: Assessment and action plan
Journal of Clinical and Translational ScienceConverting knowledge from basic research into innovations that improve clinical care requires a specialized workforce that converts a laboratory invention into a product that can be developed and tested for clinical use.
Courtney D. Hunt +6 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source