Results 191 to 200 of about 54,971,060 (296)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Medical Research Council report for the year ended 31st December 1975

, 1975
Some years ago the Medical Research Council examined the trends in research projects it supported. A wide disparity between clinical and laboratory based projects was observed.
Medical Research Council of Ireland
core  

Translational Research Could Start From the ‘Translation’ of Unmet Medical Needs to the Intended Use [PDF]

You Kyoung Lee
openalex   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Antibiofilm Technology

, 2017
The 2017 Translational Medicine Symposium was held on Feb. 27th. The symposium addressed how clinicians\u27 ideas and research results can have an impact on patient care - if they are translated into clinical practice.
Ryan Looper, PhD
core  

Models for Translational Medical Research in Israel Executive Summary

Daphne Getz, Avida Shoham, Eliezer Shein, Ella Barzani   +3 more
openalex   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Antibody-based Diagnostics

, 2017
The 2017 Translational Medicine Symposium was held on Feb. 27th. The symposium addressed how clinicians\u27 ideas and research results can have an impact on patient care - if they are translated into clinical practice.
Shawn Owen, PhD
core  

Among individuals who die of COVID-19, is the percentage who had diabetes actually higher than in those dying of other viral infections? [PDF]

Cardiovasc Diabetol Endocrinol Rep
Reddy NV, Pate V, Stürmer T, Wong R, Harper J, Reusch JE, Wilkins KJ, Tronieri J, Buse JB, Johnson SG, Bramante CT.   +10 more
europepmc   +1 more source

Guiding Preclinical Medical Students in Finding, Synthesizing, and Communicating Translational Basic Research Literature: Roles for Basic Science Research Mentors

, 2021
Steve A. Maxwell, Robin Fuchs-Young, Gregg B. Wells, Geoffrey M. Kapler, Gloria M. Conover, Sheila Green, Catherine Pepper, Barbara Gastel, David P. Huston   +8 more
openalex   +1 more source