Irish Health Research Forum meeting. Theme: should Ireland set health research priorities? [PDF]
, 2018 This report presents the proceedings of the Irish Health Research Forum on May 21st, 2018 focusing on the topic of whether Ireland should set health research ...
Medical Research Charities Group
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Recommendations on intellectual property and knowledge transfer for charity-funded research [PDF]
, 2018 A core belief of the HRCI is that charity-funded research should be used for public good; for the benefit of patients and to improve the nation’s health.
Medical Research Charities Group
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Poster Program: 2014 UMass Center for Clinical and Translational Science Research Retreat [PDF]
, 2014 List of posters presented during the Poster Session at the fifth annual UMass Center for Clinical and Translational Science Research Retreat, held Tuesday, May 20, 2014, at the Albert Sherman Center at the University of Massachusetts Medical School ...
UMass Center for Clinical and Translational Science Research Retreat
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Data protection and the health research regulations: finding a way forward: report and recommendations [PDF]
, 2019 This report presents the proceedings of the Irish Health Research Forum meeting on May 16th 2019 which focused on data protection and health research legislation, in the context of the Health Research ...
Medical Research Charities Group
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The future of translational medical humanities: bridging the data/narrative divide
, 2023 This essay argues that emerging forms of translational work in the field of medical humanities offer valuable methods for engaging with communities outside of academic settings.
Ostherr, Kirsten
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An exploratory investigation of the influence of publication on translational medicine research
Journal of Translational Medicine, 2010 Background Changes in clinical practice are brought about by the weight of clinical evidence for and against an intervention. Clinical evidence of efficacy relies on the dissemination of research results, usually by publication in medical journals which ...
Thomas Vaughan +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Medical Research Charities Group: Annual report 2016
, 2017 2016. Our role is to be the champion of medical research charities, enabling them to maximise their impact in all areas of health research and to highlight their incredibly important role in society.
Medical Research Charities Group
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