Results 131 to 140 of about 823,941 (253)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Biotechnology and Translational Medicine

Clinical and Translational Science, 2016
openaire   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Advances in Molecular and Translational Medicine: 2nd Edition. [PDF]

Int J Mol Sci
Boccellino M.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Thinking about translational medicine and traditional Chinese medicine

Journal of Translational Medicine, 2012
Zhang Boli, Zhang Junhua, Hu Jingqing
doaj   +1 more source

From Laboratory to Clinic: Translational Medicine Paradigm of Polymyxin B Nanopreparations for Overcoming Drug-Resistant Bacterial Infections. [PDF]

Int J Nanomedicine
Li N, Cao Y, Li M, Zheng D, Zhong W, Yang C.   +5 more
europepmc   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Multimodal artificial intelligence in urologic precision oncology: from algorithm to translational medicine (a systemized narrative review). [PDF]

Front Oncol
Rajaee Rizi F, Jamadi MS, Rahimi S, Bighamian M, Paidar P, Taki MJ, Bahmaie N.   +6 more
europepmc   +1 more source

Scope highlights of Annals of Translational Medicine based on a review of the history, definition, and scope of translational medicine. [PDF]

Ann Transl Med, 2023
Zhang K, Cheng Y, Peng Y, Jiang F, Zhang C, Ng CSH, Rosell R, Efird JT, Lal A, Nappi F, Weiskirchen R, Uchida S, Chua MT, D'Ambrosi R.   +13 more
europepmc   +1 more source