Results 151 to 160 of about 3,765,002 (291)

Towards universal deconvolution of tissue-level multiomics for translational medicine. [PDF]

Clin Transl Med
Liu R, Zhao T, Wang Y.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Editorial: The significance of induced pluripotent stem cells in translational medicine. [PDF]

Front Immunol
Alvarez-Palomo B, Skokowa J, Latsoudis H.   +2 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Regenerative and Translational Medicine

Journal of Orthopaedic Translation, 2016
doaj   +1 more source

Translational Medicine and Implementation Science [PDF]

São Paulo Medical Journal
Protásio Lemos da Luz, Paulo Manuel Pêgo-Fernandes   +1 more
doaj   +1 more source

Protein stereo-folding and proteostasis: A new path for clinical and translational medicine. [PDF]

Clin Transl Med
Wang Y, Qiu Y, Wang X.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Letter to the Editor for submission to journal of translational medicine contextual programming of CAR‑enhanced TIL. [PDF]

J Transl Med
Lérias JR, Kamiki J, Eduardo R, Balan V, Maeurer MJ.   +4 more
europepmc   +1 more source