Translational Medicine and Biotechnology: Turning Discovery into Impact. [PDF]
Kashani L, Akhondzadeh S.
europepmc +1 more source
Procedures in emergency medicine: oropharyngeal airway insertion
This video is part of a series of videos demonstrating common procedures performed in the Emergency Medicine setting. It was prepared by Cape Town Emergency Medicine's consultants and registrars. This short simulated video demonstrates the technique of
Oosthuizen, Almero +1 more
core
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Recent advances in the construction of humanized animal models and applications in translational medicine. [PDF]
Lyu Y, Yang YG, Hu Z.
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Equine models in translational medicine: A comparative approach to human health. [PDF]
Boozarjomehri Amnieh S, Ropka-Molik K.
europepmc +1 more source
Biotechnology and Translational Medicine
openaire +2 more sources
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Peptides as programmable molecular scaffolds: from chemical synthesis and engineering to translational medicine. [PDF]
Yuan S +5 more
europepmc +1 more source
Multifunctional nanozyme platforms in central nervous system therapies: from rational design to translational medicine. [PDF]
Niu S +13 more
europepmc +1 more source

