Results 31 to 40 of about 3,638,414 (237)
Improving translational studies: lessons from rare neuromuscular diseases [PDF]
, 2015 Animal models play a key role in the development of novel treatments for human disease. This is particularly true for rare diseases – defined as disorders that affect less than 1 in 2000 people in the human population – for which, very often, there are ...
Wells, D J
core +3 more sources
Deciphering lipid dysregulation in ALS: from mechanisms to translational medicine
Translational Neurodegeneration, 2022 Lipids, defined by low solubility in water and high solubility in nonpolar solvents, can be classified into fatty acids, glycerolipids, glycerophospholipids, sphingolipids, and sterols.
Ira Agrawal +3 more
semanticscholar +1 more source
Current Biomaterial-Based Bone Tissue Engineering and Translational Medicine
International Journal of Molecular Sciences, 2021 Bone defects cause significant socio-economic costs worldwide, while the clinical “gold standard” of bone repair, the autologous bone graft, has limitations including limited graft supply, secondary injury, chronic pain and infection.
Jingqi Qi +4 more
semanticscholar +1 more source
From biobank and data silos into a data commons: convergence to support translational medicine
Journal of Translational Medicine, 2021 To drive translational medicine, modern day biobanks need to integrate with other sources of data (clinical, genomics) to support novel data-intensive research.
Rebecca Asiimwe +9 more
semanticscholar +1 more source
A Paradigm of Translational Medicine [PDF]
, 2012 Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Korting, H. C. +3 more
core +1 more source
In vitro Models of the Blood–Brain Barrier: Tools in Translational Medicine
Frontiers in Medical Technology, 2021 Medical progress has historically depended on scientific discoveries. Until recently, science was driven by technological advancements that, once translated to the clinic, fostered new treatments and interventions.
Alberto R. Williams-Medina +2 more
semanticscholar +1 more source
Translational and Personalized Medicine
Medicine, Law & Society, 2015 The idea behind personalized medicine is to tailor health care to an individual’s unique genetic makeup. Hitherto, “one size fits all” approach was used in medicine. With the rise of personal medicine, we are moving towards a more precise, predictable and powerful medicine that is customized for each individual patient.
Kraljević-Pavelić, Sandra +2 more
openaire +4 more sources
A new vision of definition, commentary, and understanding in clinical and translational medicine
Clinical and Translational Medicine, 2012 There is growing evidence to the importance of translational science and medicine in the improvement of patient outcome, even though the definitions of translational science, translational medicine, and clinical and translational medicine need to be ...
Xiangdong Wang
doaj +1 more source
On the development and practice of translational medicine
生物医学转化, 2021 Translational medicine is an innovative research model that connects basic research and clinicalapplication. The development of translational medicine and the promotion of the transformation of results can provide advanced concepts and methods for the ...
Ayixiemuguli·Alimas, Wen Hao
doaj +1 more source
Designer Exosomes: Smart Nano-Communication Tools for Translational Medicine
Bioengineering, 2021 Exosomes are the master transporters of genes, RNAs, microRNAs, proteins, and lipids. They have applications in major diseases, including cancer, cardiovascular diseases, neurological disorders, and diabetes mellitus.
M. Harishkumar +7 more
semanticscholar +1 more source