Results 31 to 40 of about 3,424,855 (336)

Improving translational studies: lessons from rare neuromuscular diseases [PDF]

open access: yes, 2015
Animal models play a key role in the development of novel treatments for human disease. This is particularly true for rare diseases – defined as disorders that affect less than 1 in 2000 people in the human population – for which, very often, there are ...
Wells, D J
core   +3 more sources

Current Biomaterial-Based Bone Tissue Engineering and Translational Medicine

open access: yesInternational Journal of Molecular Sciences, 2021
Bone defects cause significant socio-economic costs worldwide, while the clinical “gold standard” of bone repair, the autologous bone graft, has limitations including limited graft supply, secondary injury, chronic pain and infection.
Jingqi Qi   +4 more
semanticscholar   +1 more source

From biobank and data silos into a data commons: convergence to support translational medicine

open access: yesJournal of Translational Medicine, 2021
To drive translational medicine, modern day biobanks need to integrate with other sources of data (clinical, genomics) to support novel data-intensive research.
Rebecca Asiimwe   +9 more
semanticscholar   +1 more source

Designer Exosomes: Smart Nano-Communication Tools for Translational Medicine

open access: yesBioengineering, 2021
Exosomes are the master transporters of genes, RNAs, microRNAs, proteins, and lipids. They have applications in major diseases, including cancer, cardiovascular diseases, neurological disorders, and diabetes mellitus.
M. Harishkumar   +7 more
semanticscholar   +1 more source

On the development and practice of translational medicine

open access: yes生物医学转化, 2021
Translational medicine is an innovative research model that connects basic research and clinicalapplication. The development of translational medicine and the promotion of the transformation of results can provide advanced concepts and methods for the ...
Ayixiemuguli·Alimas, Wen Hao
doaj   +1 more source

Translational and Personalized Medicine

open access: yesMedicine, Law & Society, 2015
The idea behind personalized medicine is to tailor health care to an individual’s unique genetic makeup. Hitherto, “one size fits all” approach was used in medicine. With the rise of personal medicine, we are moving towards a more precise, predictable and powerful medicine that is customized for each individual patient.
Kraljević-Pavelić, Sandra   +2 more
openaire   +4 more sources

A Paradigm of Translational Medicine [PDF]

open access: yes, 2012
Antimicrobial peptides (AMPs) are small, cationic, amphiphilic peptides with broad-spectrum microbicidal activity against both bacteria and fungi. In mammals, AMPs form the first line of host defense against infections and generally play an important ...
Korting, H. C.   +3 more
core   +1 more source

A new vision of definition, commentary, and understanding in clinical and translational medicine

open access: yesClinical and Translational Medicine, 2012
There is growing evidence to the importance of translational science and medicine in the improvement of patient outcome, even though the definitions of translational science, translational medicine, and clinical and translational medicine need to be ...
Xiangdong Wang
doaj   +1 more source

Establishment of research-oriented hospital: an important way for translational medicine development in China

open access: yesAnais da Academia Brasileira de Ciências, 2015
Globally, one of the major trends is the development of translational medicine. The traditional hospital structure could not meet the demands of translational medicine development any longer and to explore a novel hospital structure is imperative ...
MEINA LI, LULU ZHANG
doaj   +1 more source

A translational framework for public health research [PDF]

open access: yes, 2009
<p><b>Background</b></p> <p>The paradigm of translational medicine that underpins frameworks such as the Cooksey report on the funding of health research does not adequately reflect the complex reality of the public health ...
A Bradford Hill   +57 more
core   +3 more sources

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