Results 51 to 60 of about 3,765,002 (291)

Do medicine and cell biology talk to each other? A study of vocabulary similarities between fields

Brazilian Journal of Medical and Biological Research, 2021
A close interaction between basic science and applied medicine is to be expected. Therefore, it is important to measure how far apart the field of cell biology and medicine are.
S. Azevedo, M.R. Seixas, A.D. Jurberg, C. Mermelstein, M.L. Costa   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

INTERACTOMICS IN TRANSLATIONAL MEDICINE

Сеченовский вестник, 2018
The article describes the place of interactomics in translational medicine. The approaches and methods used for the detection of protein-protein interactions and the construction of interactomes are described.
A. I. Glukhov, Z. A. Khuchua, G. K. Grizunova, D. V. Astakhov, M. I. Danilevskiy   +4 more
doaj  

Building a Professional Identity and an Academic Career Track in Translational Medicine [PDF]

, 2019
Biomedical scientists aim to contribute to further understanding of disease pathogenesis and to develop new diagnostic and therapeutic tools that relieve disease burden.
Lindemans, Caroline A, Rosenblum, Norman D., Hunter, P., Gomez-Ospina, N, Dijk, S.J. (Sabine) van, Rosenblum, ND, van Rossum, Annemarie M C, Hunter, Patricia, van Rossum, AMC, van Dijk, Sabine J., Lindemans, Caroline A., Gomez-Ospina, N., Domenighetti, Andrea A., Melotte, Veerle, Domenighetti, AA, Gomez-Ospina, Natalia, van Rossum, Annemarie, Rosenblum, Norman D, Rosenblum, N.D., van Dijk, Sabine J, Lindemans, CA, van Dijk, SJ, Hunter, P, Rossum, A.M.C. (Annemarie) van, Melotte, V, van Rossum, Annemarie M. C., Domenighetti, A.A., Melotte, V., Domenighetti, Andrea A   +28 more
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Enhancing the training of translational researchers is the essential way to accelerate the translational medicine of acupuncture and moxibustion

针刺研究, 2023
Talent team construction is the foundation of translational medicine research of acupuncture and moxibustion. In college education and continuing education after graduation, with the idea of translational medicine, it is necessary to cultivate both the ...
FANG Jian-qiao
doaj   +2 more sources

Regenerative technologies to bed side: Evolving the regulatory framework

Journal of Orthopaedic Translation, 2017
There are high expectations for the clinical application of regenerative medicine technologies to treat musculoskeletal disorders. However, there are still big hurdles in bringing cell-based products to the market, mainly due to strict regulatory ...
Daisuke Sakai, Jordy Schol, Casper B. Foldager, Masato Sato, Masahiko Watanabe   +4 more
doaj   +1 more source

The international effort: building the bridge for Translational Medicine: Report of the 1st International Conference of Translational Medicine (ICTM) [PDF]

, 2012
Background: Supported by the International Society for Translational Medicine (ISTM), Wenzhou Medical College and the First Affiliated Hospital of Wenzhou Medical College, the International Conference on Translational Medicine (ICTM) was held on October ...
Coico, Richard, Liebman, Michael N, Christiani, David, Giuseppe Marraro, Ena Wang, David Christiani, Francesco M Marincola, Wei Wang, Marincola, Francesco M, Markus Ege, Xiangdong Wang, Gao, Hongwei, Marraro, Giuseppe, Jinglin Xia, Spada, Claudio, Hongwei Gao, Yong‐Xiao Wang, Thomas Fehniger, Marko-Varga, Gyorgy, Wang, Yong-Xiao, Wang, Xiangdong, Wang, Ena, Richard Coico, Ege, Markus, Andersson, Roland, William CS Cho, Xiaoming Chen, Wang, Wei, Jeffery Drazen, Xia, Jinglin, Popescu, Laurentiu M, Kunlin Jin, Claudio Spada, Chen, Xiaoming, Qu, Jia, Drazen, Jeffery, Lopez, Elena, Cho, William CS, Roland Andersson, Gyorgy Marko‐Varga, Fehniger, Thomas, Yong-Xiao Wang, Elena Lopez, Shahzad, Aamir, Jin, Kunlin, Lopez, Maria, Aamir Shahzad, Laurentiu M Popescu, Gyorgy Marko-Varga, Jia Qu, Michael N Liebman   +50 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Challenge in the new era: Translational medicine in gastrointestinal endoscopy and early cancer

Chronic Diseases and Translational Medicine, 2019
Translational medicine is a new medical model that has emerged over the past 20 years and is dedicated to bridging the gap between basic and clinical research.
Yang Yu, Yan-Hua Yin, Li Min, Sheng-Tao Zhu, Peng Li, Shu-Tian Zhang   +5 more
doaj   +1 more source