Results 31 to 40 of about 3,765,002 (291)
Statistical Methods in Translational Medicine
Journal of the Formosan Medical Association, 2008 This study focuses on strategies and statistical considerations for assessment of translation in language (e.g. translation of case report forms in multinational clinical trials), information (e.g.
Shein-Chung Chow, Siu-Keung Tse, Min Lin
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, 2012 BACKGROUND: Clinical translational medicine (CTM) is an emerging area comprising multidisciplinary research from basic science to medical applications and entails a close collaboration among hospital, academia and industry. FINDINGS: This Session focused
Wang, X +12 more
core +1 more source
Journal of International Medical Research, 2019 Objective The study aim was to evaluate the knowledge and attitudes of hospital health personnel toward translational medicine. Methods We conducted a cross-sectional survey from July 2013 to September 2013 with a representative sample of 1690 health ...
Li Meina +4 more
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Translational Medicine - doing it backwards
Journal of Translational Medicine, 2010 In recent years the concept of "translational medicine" has been advanced in an attempt to catalyze the medical applications of basic biomedical research.
Schechter Alan N +2 more
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Translational Medicine: A two-way road
Journal of Translational Medicine, 2003 The purpose of translational research is to test, in humans, novel therapeutic strategies developed through experimentation. Translational research should be regarded as a two-way road: Bench to Bedside and Bedside to Bench.
Marincola Francesco M
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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AAAS joins the Translational Medicine family
Journal of Translational Medicine, 2009 The AAAS has announced the launch of Science Translational Medicine. This is further and critical recognition of this discipline and we are deeply gratified that translational medicine has risen to the level of recognition by one of the world's most ...
Marincola Francesco M, Brander Christian
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source