Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Bibliography of English translations from medieval sources, 1943-1967
Supplement to: Bibliography of English translations from medieval sources / by C. P. Farrar and A. P. Evans.
Ferguson, Mary Anne. +1 more
core
Visual motion does not bias gravity-referenced vestibular coding in the primate cerebellar nodulus and uvula. [PDF]
Gómez LJ +3 more
europepmc +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Cultural adaptation of the Work Disability Functional Assessment Battery (WD-FAB) into German (Germany): hybrid application of two adaptation approaches. [PDF]
Feng YS +8 more
europepmc +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Benchmarking AI-Powered Translation of the EQ-5D-5L Patient-Reported Outcome Measure Using Automated Metrics: Comparative Evaluation Study. [PDF]
Vashisht H, Ward T, Muehlhausen W.
europepmc +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Impact of translation availability on the patient voice in clinical trials: commentary. [PDF]
Kuliś D +5 more
europepmc +1 more source

