Results 111 to 120 of about 102,786 (302)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Corpora in Translator Education: An Introduction
, 2014 The use of corpora to verify how words are used in context can be particularly useful in areas of languages for special purposes (LSPs) and terminology.
Stewart D., Bernardini S., Zanettin F.
core +1 more source
The translatics of translation
Journal of Modern Languages, 2017 The project on which this paper is based offers Translatics as a theory of translation which is designed and developed as an alternative that challenges the mainstream views currently held within translation studies. To familiarize the readers with Translatics, an attempt will be made to provide and describe its foundational key concepts and features ...
openaire +8 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Translator: Expert of what translator training and the changing/changeful identity of the translator
, 2013 The aim of this paper is to trace the contemporary perceptions/definitions of the translator and translation in Turkey where the translation profession is not a legally regulated profession.
Öner, Senem
core +1 more source
, 2019 The study reported in this updated chapter pursues two main pedagogical objectives. The first is to increase our understanding of co-emergent learning effects and feedback flows in an authentic collaborative translation project at our institute, with a ...
Brändli, Barbara, Massey, Gary
core +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Item 192, Side A only: Interview with Siming Askim, recorded on Kranket Island, Madang, Papua New Guinea, 7 September 1981. Translator: Wilson Walsa. -- Item 193, Side A. 1. Continuation of interview with Siming Askim, recorded on Kranket Island, Madang,
Interviewee: Askim Siming +4 more
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