Results 161 to 170 of about 33,857 (218)

Discovering mythorealism: A corpus stylistic analysis of Yan Lianke's novels in English. [PDF]

PLoS One
Zhang Y, Zhao C.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A family like this. [PDF]

CMAJ
Cheng A.
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A corpus-based analysis on the use of MAKE in sinologist Cyril Birch's English version of Mistress and Maid (Jiaohongji). [PDF]

PLoS One
Yu C, Wu Y.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Announcing the Biomedical Data Translator: Initial Public Release. [PDF]

Clin Transl Sci
Fecho K, Glusman G, Baranzini SE, Bizon C, Brush M, Byrd W, Chung L, Crouse A, Deutsch E, Dumontier M, Foksinska A, Hadlock J, He K, Huang S, Hubal R, Hyde GM, Israni S, Kenmogne K, Koslicki D, Marcette JD, Mathe EA, Mesbah A, Moxon SAT, Mungall CJ, Osborne J, Pasfield C, Qin G, Ramsey SA, Reese J, Roach JC, Rose R, Soman K, Su AI, Ta C, Vaidya G, Weber R, Wei Q, Williams M, Wu C, Xu C, Yakaboski C, Biomedical Data Translator Consortium.   +41 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Translation and Preliminary Psychometric Evaluation of the Arabic 5-Item Dry Eye Questionnaire: A Reliability Study in Healthy Young Adults. [PDF]

Clin Ophthalmol
Al Farhan H, Aldawasri SA, Al Salloum AM, Anazi NS, Alarify H, Al-Otaibi WM.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source