Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Synthetic CRISPR Networks Driven by Transcription Factors via Structure-Switching DNA Translators. [PDF]
Capelli L +3 more
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Development and validation of Thai version of female sexual function index for a Thai population. [PDF]
Homsangpradit K +2 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Integrating human-AI collaboration into translation education: A comprehensive protocol for assessment, diagnosis, and strategy development. [PDF]
Ren X, Wang R.
europepmc +1 more source
E-Visit Usage Among a Population of Young Adults. [PDF]
Eaton A, Prausnitz SR, Tran HN.
europepmc +1 more source
Evaluation of Generative Artificial Intelligence Implementation Impacts in Social and Health Care Language Translation: Mixed Methods Case Study. [PDF]
Martikainen M +3 more
europepmc +1 more source
Translation and Pilot Validation of the EORTC QLQ-SH22 Module in Tamil, Telugu, and Malayalam for Assessing Sexual Health-Related Quality of Life in Cancer Patients. [PDF]
Yadala A +10 more
europepmc +1 more source
Esotropia Missed During Pre-health Checkup Screening With the Spot Vision Screener: A Case Series. [PDF]
Fuseya K +7 more
europepmc +1 more source

