Results 151 to 160 of about 1,015,611 (339)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu +5 more
wiley +1 more source
Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase. [PDF]
, 2019 Bacterial ClpB and yeast Hsp104 are homologous Hsp100 protein disaggregases that serve critical functions in proteostasis by solubilizing protein aggregates.
Bart, Stephen M +8 more
core
Cell-Free Synthesis of Functional and Endotoxin-Free Antibody Fab Fragments by Translocation into Microsomes [PDF]
, 2012 Helmut Merk +4 more
openalex +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Single Stranded DNA Translocation Through A Nanopore: A Master Equation Approach
, 2003 We study voltage driven translocation of a single stranded (ss) DNA through a membrane channel. Our model, based on a master equation (ME) approach, investigates the probability density function (pdf) of the translocation times, and shows that it can be ...
A. Bar-Haim +15 more
core +1 more source
Structural basis for substrate selection by the translocation and assembly module of the β‐barrel assembly machinery [PDF]
, 2017 Rebecca S. Bamert +12 more
openalex +1 more source
Advanced Biology, EarlyView.The article explores the discovery of unusually large, ring‐shaped ESCRT protein structures formed by immune and stromal cells. It investigates their formation, composition, and potential roles in immune synapse formation. The findings challenge assumptions about their function in immunological synapses, suggesting an exclusive role in maintaining ...
Anthi Psoma +3 more
wiley +1 more source
Fungal Translocation: A Driving Force Behind the Occurrence of Non-AIDS Events? [PDF]
, 2019 Martin Hoenigl
openalex +1 more source
Advanced Functional Materials, EarlyView.A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo +13 more
wiley +1 more source