Results 11 to 20 of about 1,246,248 (385)

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

open access: yesRetrovirology, 2006
Chronic activation of the immune system is a hallmark of progressive HIV infection and better predicts disease outcome than plasma viral load, yet its etiology remains obscure.
J. Brenchley
semanticscholar   +2 more sources

Intestinal Barrier Dysfunction, LPS Translocation, and Disease Development

open access: yesJournal of the Endocrine Society, 2020
The intestinal barrier is complex and consists of multiple layers, and it provides a physical and functional barrier to the transport of luminal contents to systemic circulation.
Siddhartha S Ghosh   +3 more
semanticscholar   +1 more source

Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

open access: yesNature Cell Biology, 2020
Immunotherapies that target programmed cell death protein 1 (PD-1) and its ligand PD-L1 as well as cytotoxic T-lymphocyte-associated protein 4 (CTLA4) have shown impressive clinical outcomes for multiple tumours.
Yang Gao   +26 more
semanticscholar   +1 more source

Short and long distance translocations: Movement and survival in eastern box turtles (_Terrapene carolina carolina_) [PDF]

open access: yes, 2009
*Background/Question/Methods* Human development represents a serious threat to wildlife populations through continued habitat loss and incidental mortality from construction activities.
Patrick W. Cain   +2 more
core   +2 more sources

Inositol phospholipids: Translocation, translocation, translocation … [PDF]

open access: yesCurrent Biology, 1998
The pleckstrin homology (PH) domains of a number of proteins have been found to interact in vitro with inositol phospholipids; recent experiments show that these interactions may be important in directing protein translocation to specific parts of the cell following stimulus-induced lipid breakdown or synthesis.
openaire   +2 more sources

Influence of polymer-pore interactions on translocation [PDF]

open access: yes, 2007
We investigate the influence of polymer-pore interactions on the translocation dynamics using Langevin dynamics simulations. An attractive interaction can greatly improve translocation probability.
Aniket Bhattacharya   +8 more
core   +2 more sources

Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex [PDF]

open access: yes, 2012
The bacterial ATPase SecA and protein channel complex SecYEG form the core of an essential protein translocation machinery. The nature of the conformational changes induced by each stage of the hydrolytic cycle of ATP and how they are coupled to protein ...
Alice Robson   +42 more
core   +2 more sources

A case of pervasive developmental disorder with chromosomal translocation 1-4 Um caso de transtorno invasivo do desenvolvimento com translocação cromossômica 1-4

open access: yesArquivos de Neuro-Psiquiatria, 2007
A 5-year-old girl is described as pervasive developmental disorder associated to chromosome 1-4 translocation, being such association not described till this moment in specialized literature.Descrevemos uma menina de 5 anos de idade portadora de ...
Luciana G. Tarelho   +1 more
doaj   +1 more source

Out of their depth: The successful use of cultured subtidal mussels for intertidal restoration

open access: yesConservation Science and Practice, 2023
Ecosystem restoration has proliferated across the globe to combat widespread ecosystem decline. Translocations of viable individuals into degraded habitats form a core component of restoration efforts, but the selection of source populations poses ...
Trevyn A. Toone   +4 more
doaj   +1 more source

Functioning of potassium and magnesium in photosynthesis, photosynthate translocation and photoprotection.

open access: yesPhysiologia Plantarum : An International Journal for Plant Biology, 2018
Potassium (K) and magnesium (Mg) are mineral nutrients that are required in large quantities by plants. Both elements critically contribute to the process of photosynthesis and the subsequent long-distance transport of photoassimilates. If K or Mg is not
Merle Tränkner   +2 more
semanticscholar   +1 more source

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