Results 321 to 330 of about 1,246,248 (385)

A stiffness-gated YAP-β-catenin axis orchestrates AXIN2 expression in metastatic breast cancer. [PDF]

iScience
Wu Y, Su Z, Ge C, Barooj S, Hirota JA, Geng F.   +5 more
europepmc   +1 more source

Lactylated SPTAN1 Accelerates Hepatocellular Carcinoma Progression by Promoting NOTCH1/HES1 Activation and Immunosuppression

Advanced Science, EarlyView.
This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang, Dongjie Ye, Linqing Wu, Jiayu Liu, Banglun Pan, Zhu Zhang, Xiaoxia Zhang, Yuxin Yao, Nanhong Tang   +8 more
wiley   +1 more source

Nuclear translocation of Cx43 promotes to CRC progression and associates with β-catenin accumulation. [PDF]

Cancer Biol Ther
Wang S, Zhu Z, Zhu Y, Tan J, Shen X, Wen H, Wu J, Xu J, Zheng J, Chen Y, Yang W, Deng H.   +11 more
europepmc   +1 more source

Activated CaMKIIδ translocates to the RyR nanodomain in cardiomyocytes. [PDF]

Cardiovasc Res
Bergan-Dahl A, Carlson CR, Laasmaa M, Subramanian H, Basson A, Li J, Hasic A, Lunde M, Ugland H, Manfra O, Klussmann E, Bossuyt J, Bers DM, Nikolaev VO, Louch WE, Shen X.   +15 more
europepmc   +1 more source

Solid-State Nanopore Single-Molecule Analysis of SARS-CoV-2 N Protein: From Interaction Exploration to Small-Molecule Antagonism. [PDF]

Sensors (Basel)
Zeng X, Leng S, Ma W, Wang Z, Zhang H, Feng X, Li J, Wang J, Weng T, Tian R, He S, Fang S, Yin B, Liang L, Yin Y, Wang D.   +15 more
europepmc   +1 more source

TLX1 translocation variants and enhancer hijacking influence clinical outcome in T-cell acute lymphoblastic leukemia. [PDF]

Hemasphere
Balducci E, Steimlé T, Cieslak A, Charbonnier G, Pinton A, Simonin M, Smith C, Louis V, Féroul M, Delafoy M, Kaltenbach S, Bidet A, Grange B, Rigollet L, Villarese P, Touzart A, Dombret H, Baruchel A, Boissel N, Asnafi V.   +19 more
europepmc   +1 more source

Assembly of Macromolecular Complexes in the Whole-Cell Model of a Minimal Cell. [PDF]

J Phys Chem B
Fu E, Thornburg ZR, Brier TA, Wei R, Yuan B, Gilbert BR, Wang S, Luthey-Schulten Z.   +7 more
europepmc   +1 more source

Reviewer #1 (Public Review): Rapid translocation of NGR proteins drives polarization of PIN-activating D6 protein kinase during root gravitropism

Ivan Kulich, Júlia Schmid, Anastasia Teplova, Linlin Qi, Jiřı́ Friml   +4 more
openalex   +1 more source

An open axial channel of the AAA ClpXP protease enhances degradation of specific classes of protein substrates. [PDF]

Protein Sci
Lyu Y, Bolstad I, Davis JH, Sauer RT, Ghanbarpour A.   +4 more
europepmc   +1 more source