Results 341 to 350 of about 1,195,157 (388)

Genetic rescue of Florida panthers reduced homozygosity but did not swamp ancestral genotypes. [PDF]

open access: yesProc Natl Acad Sci U S A
Aguilar-Gómez D   +8 more
europepmc   +1 more source

Emodin Alleviates Sepsis‐Induced Multiorgan Damage by Inhibiting NETosis through Targeting Neutrophils BCL‐10

open access: yesAdvanced Science, EarlyView.
Emodin targets BCL‐10 to modulate the BCL‐10/MALT1 complex, thereby suppressing NF‐κB activation and significantly exerting multiorgan protective effects in sepsis. Abstract Sepsis is a life‐threatening condition caused by dysregulated host responses to infection, characterized by excessive inflammation and abnormal coagulation.
Xiaolong Xu   +16 more
wiley   +1 more source

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

open access: yesAdvanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang   +11 more
wiley   +1 more source

Forest Density Drives Survival and Trait Variation in South European Understorey Species: A Continental-Scale Translocation Experiment. [PDF]

open access: yesEcol Lett
Gasperini C   +9 more
europepmc   +1 more source

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