Results 61 to 70 of about 4,630,594 (315)

The Bioremediation Potential of Perennial Ryegrass (Lolium perenne L.) in the Presence of Cadmium or Copper

Stresses
Our main goal was to determine whether the accumulation of Cd and Cu is harmful for L. perenne or whether this plant can be used in the bioremediation, e.g., of wastewaters or contaminated soils.
Pavlína Eliška Šotek, Marianna Molnárová, Ammara Nawaz, Agáta Fargašová   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Protein Targeting to the Bacterial Cytoplasmic Membrane [PDF]

, 1999
Proteins that perform their activity within the cytoplasmic membrane or outside this cell boundary must be targeted to the translocation site prior to their insertion and/or translocation.
Fekkes, Peter, Fekkes, Peter,, Driessen, Arnold J.M.,, Driessen, Arnold J.M.   +3 more
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Effect of Treated Wastewater Irrigation on the Accumulation and Transfer of Heavy Metals in Lemon Trees Cultivated in Arid Environment

Horticulturae, 2022
The Middle East is considered as one of the driest regions of the world and the use of municipal-treated wastewater (TWW) for agricultural purposes is needed.
Randa N. Albdaiwi, Jehad S. Al-Hawadi, Ziad B. Al-Rawashdeh, Khaled A. Al-Habahbeh, Jamal Y. Ayad, Rabea S. Al-Sayaydeh   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Cadmium accumulation and tolerance in Populus nigra and Salix alba

Biologia Plantarum, 2011
Rooted cuttings of Populus nigra L. clone Poli and Salix alba L. clone SS5 were treated for three weeks with 50 μM CdSO4 in nutrient solution. The willow showed a far higher Cd tolerance, expressed as tolerance index (Ti), than the poplar in both roots ...
M. Zacchini, V. Iori, G. Scarascia Mugnozza, F. Pietrini, A. Massacci   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Biochar and Trehalose Co-Application: A Sustainable Strategy for Alleviating Lead Toxicity in Rice

Plants
Lead (Pb) is a common contaminant that causes serious health and environmental problems. Thus, appropriate environmentally friendly and efficient techniques must be developed to remediate Pb in soils.
Yingfen Yang, Li Liu, Haibo Xiong, Tianju Wang, Jun Yang, Wenpeng Wang, Areej A. Al-Khalaf, Zhuhua Wang, Waqar Ahmed   +8 more
doaj   +1 more source