Results 111 to 120 of about 12,426 (266)

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura   +14 more
wiley   +1 more source

Noninvasive Glucose Detection with Biodegradable Electrodes from Rice Starch Functionalized with a Carbon Quantum Dot/Nickel Oxide Nanocomposite

open access: yesAnalysis &Sensing, EarlyView.
The graphical abstract shows an eco‐friendly approach to fabricating a biodegradable electrochemical sensor. Carbon quantum dot/nickel oxide (CQD/NiO) nanocomposites are synthesized using Aloe arborescens leaf extract, which served as a natural reducing and stabilizing agent.
Nokwanda Ngema   +3 more
wiley   +1 more source

Bioconvection Darcy–Forchheimer Flow of Ree‐Eyring Nanofluid Over a Riga Plate With Arrhenius Activation Energy and Viscous Dissipation

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This work examines the intricate interactions of heat radiation, viscous dissipation, the Cattaneo–Christov thermal model, gyrotactic microorganisms, Arrhenius activation energy, and Darcy–Forchheimer flow affecting Ree‐Eyring nanofluid behavior across a Riga plate.
M. Vinodkumar Reddy   +4 more
wiley   +1 more source

Boron deficiency responses in maize (Zea mays L.) roots

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView., 2023
Abstract Background Boron (B) is an essential micronutrient for plants. Dicot plants respond to insufficient B supply by altering root architecture and root hair growth. How root systems of rather low‐B demanding monocot species such as maize (Zea mays L.) respond to B deficiency in terra has not been experimentally resolved, yet.
Manuela Désirée Bienert   +5 more
wiley   +1 more source

From Hemp Bast to Lyocell Fiber: Sustainable Process Optimization for Lyocell‐Grade Dissolving Pulp

open access: yesJournal of Applied Polymer Science, EarlyView.
This study presents a sustainable method to produce lyocell‐grade dissolving pulp from Canadian hemp bast fibers. A simplified alkali‐chelation‐bleaching process, free from sulfur and chlorine, yielded high α‐cellulose pulp with low lignin and hemicellulose content. The pulp was successfully spun into continuous hemp‐based lyocell fibers, demonstrating
Md Abu Sayed   +8 more
wiley   +1 more source

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