Results 41 to 50 of about 1,679,372 (245)
Philosophical Transactions of the Royal Society B: Biological Sciences, 2017 Parasites and pathogens (hereafter referred to collectively as parasites) can have devastating consequences for the individuals they infect, with Ebola and Zika being (at the time of writing) only the most recent examples in a very long list.
Joanne Lello, Andy Fenton
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Machines, 2023 In modeling the characteristics of a discharging valve in a hydrodynamic retarder, it is commonly required to determine the value of the flow area to calculate the force on the spool. However, the flow area often relies heavily on empirical or simulation
Wei Wei +6 more
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Reflection–transmission algebras [PDF]
Journal of Physics A: Mathematical and General, 2003 Inspired by factorized scattering from delta-type impurities in (1+1)-dimensional space-time, we propose and analyse a generalization of the Zamolodchikov-Faddeev algebra. Distinguished elements of the new algebra, called reflection and transmission generators, encode the particle-impurity interactions.
Mintchev, M., Ragoucy, E., Sorba, P.
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Design and Development of 4500 V Trench Gate IGBT
Zhongguo dianli, 2020 In this paper, a 4500 V trench gate IGBT chip was developed, so as to improve the single chip current density as well as to master the technology of high voltage trench gate IGBT.
Li LI +4 more
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Strategic Information Transmission [PDF]
Econometrica, 1982 This paper develops a model of strategic communication, in which a better-informed Sender (S) sends a possibly noisy signal to a Receiver (R), who then takes an action that determines the welfare of both. We characterize the set of Bayesian Nash equilibria under standard assumptions, and show that equilibrium signaling always takes a strikingly simple ...
Crawford, Vincent P, Sobel, Joel
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
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IEEE Access, 2019 Cascading faults of computer numerical control machine tools will lead to frequent machine faults, but an effective fault analysis and control strategy can significantly reduce the frequency of such cascading faults.
Guangquan Huang +4 more
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MulTNet: A Multi-Scale Transformer Network for Marine Image Segmentation toward Fishing
Sensors, 2022 Image segmentation plays an important role in the sensing systems of autonomous underwater vehicles for fishing. Via accurately perceiving the marine organisms and surrounding environment, the automatic catch of marine products can be implemented ...
Xi Xu +4 more
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