Results 51 to 60 of about 3,312,918 (299)
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Sugar Lego: gene composition of bacterial carbohydrate metabolism genomic loci
Background Bacterial carbohydrate metabolism is extremely diverse, since carbohydrates serve as a major energy source and are involved in a variety of cellular processes.
Anna Kaznadzey +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
WEST Associates Transmission Line
Document: "WEST Associates transmission line map",1966 ...
Western Energy Supply and Transmission (WEST) Associates (?)
core +2 more sources
Silicon nitride powder is a crucial raw material for fabricating silicon nitride ceramics, with its properties exerting a decisive influence on the final product’s performance.
Jingkai Nie +6 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Efficient transient simulation of transmission lines [PDF]
The paper focuses on revealing the salient structural aspects of a new transmission-line model with a view to exploiting them for gains in efficiency and accuracy. The new transmission-line model has as its basis the Telegraphers Equations but the manner
Condon, Marissa, M. Condon
core +2 more sources
Transmission et théories des littératures francophones
Du Maghreb à la Polynésie, en passant par les Amériques, l’Afrique et l’Europe, des voix multiples font entendre leur attachement à des littératures francophones et à une langue qu’elles abordent sans idéalisme, dans l’espoir d’ouvrir à un métissage à la
core +2 more sources
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Tuberculosis Transmission by Patients with Smear- Negative Pulmonary Tuberculosis in a Large Cohort in The Netherlands [PDF]
Background. Sputum smear microscopy is commonly used for diagnosing tuberculosis (TB). Although patients with sputum smear-negative TB are less infectious than patients with smear-positive TB, they also contribute to TB transmission.
Smear-Negative +3 more
core

