Results 41 to 50 of about 3,409,157 (307)

Trans2express – de novo transcriptome assembly pipeline optimized for gene expression analysis

Plant Methods
Background As genomes of many eukaryotic species, especially plants, are large and complex, their de novo sequencing and assembly is still a difficult task despite progress in sequencing technologies.
Aleksandra M. Kasianova, Aleksey A. Penin, Mikhail I. Schelkunov, Artem S. Kasianov, Maria D. Logacheva, Anna V. Klepikova   +5 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Research on transmission control method of tension tower hydraulic tension device based on PLC

Journal of Applied Science and Engineering, 2023
Using the traditional method to control the transmission process of the tension tower hydraulic tightening device, there is a problem of slow speed step response in the range of device operating speed from 12km/h to 32km/h.
Jinghui Zhang, Quanjun Yin, Haixing Yang, Zhongquan Jiao   +3 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Comparative genomics and evolution of regulons of the LacI-family transcription factors

Frontiers in Microbiology, 2014
DNA-binding transcription factors (TFs) are essential components of transcriptional regulatory networks in Bacteria. LacI-family TFs (LacI-TFs) are broadly distributed among certain lineages of bacteria. The majority of characterized LacI-TFs sense sugar
Dmitry A Ravcheev, Matvei S Khoroshkin, Olga N Laikova, Olga V Tsoy, Natalia V Sernova, Svetlana A Petrova, Aleksandra B Rakhmaninova, Pavel S Novichkov, Mikhail S Gelfand, Mikhail S Gelfand, Dmitry A Rodionov, Dmitry A Rodionov   +11 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Comparative evaluation of multiple machine learning models for power system fault diagnosis

Frontiers in Energy Research
BackgroundAs power systems continue to expand in scale and complexity, fault types have become increasingly diverse and their propagation mechanisms more difficult to capture through conventional rule-based methods.
Huiwei Liu, Pengjie He, Ziqiang Lu, Jie Li, Ziying Lu, Jinchuan Jia   +5 more
doaj   +1 more source

Experimental verification of mobility modeling for N-polar GaN HEMTs [PDF]

AIP Advances
N-polar GaN high-electron-mobility transistors (HEMTs) show unique transfer characteristics originating from the band structure related to the inverted HEMTs, and some scattering mechanisms are suggested theoretically.
Akira Mukai, Shigeki Yoshida, Junya Yaita, Akihiro Hayasaka, Maui Hino, Junji Kotani, Kozo Makiyama, Ken Nakata   +7 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Evaluation of the Friendliness of Live Working on Distribution Network Based on AHP-EWM Method

International Transactions on Electrical Energy Systems
The traditional evaluation of the friendliness of live working on distribution networks relies on construction experience. This approach is not only susceptible to individual subjective factors, with the inherent risk of judgment errors, but also ...
Teng Yang, Wen-Juan Zhang, Xu-Qiang Gong, Yu-Hang Ou, Li Huang   +4 more
doaj   +1 more source