Results 41 to 50 of about 1,391,604 (337)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Effects of Wear, Backlash, and Bearing Clearance on Dynamic Characteristics of a Spur Gear System

open access: yesIEEE Access, 2019
A six-degree-of-freedom gear pair torsional vibration model considering time-varying stiffness, damping, dynamic backlash, bearing radial clearance and comprehensive wear of the tooth surface is established by using the lumped mass method in this paper ...
Ying-Kui Gu   +3 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Dynamic Characteristics Analysis and Optimization Design of Two-Stage Helix Planetary Reducer for Robots

open access: yesMachines
The dynamic characteristics of high-precision planetary reducers in terms of vibration response and dynamic transmission error have a significant impact on positioning accuracy and service life.
Wenzhao Lin   +4 more
doaj   +1 more source

Explores for the source of the gears in traditional Japanese clock (Wadokei)

open access: yesNihon Kikai Gakkai ronbunshu, 2017
The purpose of this study is to understand the nature of one of the oldest gears used in traditional Japanese clock. Today's gear manufacturing technology in Japan came mostly from Europe and America, but we do not know exactly, when and how the ...
Akio UEDA   +4 more
doaj   +1 more source

A Novel Model of an S-Shaped Tooth Profile Gear Pair with a Few Pinion Teeth and Tooth Contact Analysis Considering Shaft Misalignments

open access: yesApplied Sciences, 2023
Due to the special meshing of convex and concave tooth profiles, an S-shaped tooth profile gear with a few teeth has the advantage of reducing the contact stress and improving the contact ratio.
Wei Chen   +3 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Optimal Measurement Speed and Its Determination Method in the Transmission Precision Evaluation of Precision Reducers

open access: yesApplied Sciences, 2019
Transmission error is the key index for characterizing the transmission precision of precision reducers, and its accurate measurement is significant for the precision evaluation of precision reducers.
Hang Xu, Zhaoyao Shi, Bo Yu, Hui Wang
doaj   +1 more source

Dynamic Torsional Stiffness of Reducers and Its Testing Method

open access: yesApplied Sciences, 2023
The torsional stiffness of the reducer is commonly assumed to be static and tested using the hysteresis curve method. However, practical engineering experience shows that the torsional stiffness is dynamic rather than static, and the hysteresis curve ...
Huiming Cheng   +3 more
doaj   +1 more source

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