Results 41 to 50 of about 1,396,285 (293)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A Study on the High Efficiency and Low Noise Design of Electric Industrial Gearboxes [PDF]

한국정밀공학회지
Development and research on electric vehicles in power transmission system are increasing as the demand for eco-friendly and autonomous vehicles increases across the industry.
Nam Yong Kim, Jin-Uk Baek, Sung Ki Lyu
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Basic study on transmission error for gear made from different metals laminated in width direction to provide rigidity distribution

Mechanical Engineering Journal, 2023
To improve the load characteristics of the transmission error for helical gears, a gear made of laminated materials is proposed. The gear has three layers in which metals with different rigidities are laminated in the tooth width direction. The layers on
Fumitaka YOSHIZUMI, Takayuki AOYAMA, Yoshikatsu SHIBATA   +2 more
doaj   +1 more source

An efficient error resilience scheme based on wyner-ziv coding for region-of-Interest protection of wavelet based video transmission [PDF]

, 2008
In this paper, we propose a bandwidth efficient error resilience scheme for wavelet based video transmission over wireless channel by introducing an additional Wyner-Ziv (WZ) stream to protect region of interest (ROI) in a frame.
Cosmas, J, Loo, KK, Yip, PY, Zhuo, X
core  

Short Packets over Block-Memoryless Fading Channels: Pilot-Assisted or Noncoherent Transmission? [PDF]

, 2017
We present nonasymptotic upper and lower bounds on the maximum coding rate achievable when transmitting short packets over a Rician memoryless block-fading channel for a given requirement on the packet error probability.
Coşkun, Mustafa C., Durisi, Giuseppe, Liva, Gianluigi, Ström, Erik G., Östman, Johan   +4 more
core   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Dynamic Characteristics Analysis and Optimization Design of Two-Stage Helix Planetary Reducer for Robots

Machines
The dynamic characteristics of high-precision planetary reducers in terms of vibration response and dynamic transmission error have a significant impact on positioning accuracy and service life.
Wenzhao Lin, Dongdong Chang, Hao Li, Junhua Chen, Fangping Huang   +4 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source