Results 51 to 60 of about 313,930 (265)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Configuration Analysis of the ERS Points in Large-Volume Metrology System

Sensors, 2015
In aircraft assembly, multiple laser trackers are used simultaneously to measure large-scale aircraft components. To combine the independent measurements, the transformation matrices between the laser trackers’ coordinate systems and the assembly ...
Zhangjun Jin, Cijun Yu, Jiangxiong Li, Yinglin Ke   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Research on Smart Power Sales Strategy Considering Load Forecasting and Optimal Allocation of Energy Storage System in China

Energies, 2023
With the deepening reform of the power system, power sales companies need to adopt new power sales strategies to provide customers with better economic marketing solutions.
Hongli Liu, Luoqi Wang, Ji Li, Lei Shao, Delong Zhang   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Analysis of Vibration Characteristics of Electro-hydraulic Driven 3-UPS/S Parallel Stabilization Platform

Chinese Journal of Mechanical Engineering
With the development of fluid-power transmission and control technology, electro-hydraulic-driven technology can significantly improve the load-carrying capacity, stiffness, and control accuracy of stabilization platforms.
Xiaoming Yuan, Weiqi Wang, Haodong Pang, Lijie Zhang   +3 more
doaj   +1 more source

A High-Pressure Bi-Directional Cycloid Rotor Flowmeter

Sensors, 2014
The measurement of the flow rate of various liquids and gases is critical in industrial automation. Rotary positive displacement meters (rotary PD meters) are highly accurate flowmeters that are widely employed in engineering applications, especially in ...
Shuo Liu, Fan Ding, Chuan Ding, Zaipeng Man   +3 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Analysis and Optimization of Multi-Physical Field Coupling in Boom Flow Channel of Excavator Multiway Valves

Machines
The multiway valve is the core control element of the hydraulic system in construction machinery, such as excavators. Its complex internal structure, especially the flow channels, significantly impacts the machine’s efficiency and reliability. This study
Ze Zheng, Nuoyan Chen, Xiaoming Yuan, Zongjin Zhang, Xiaoping Liu, Zhiao Ma   +5 more
doaj   +1 more source

ACTOR: Adaptive Control of Transmission Power in RPL

Sensors
RPL—Routing Protocol for Low-Power and Lossy Networks (usually pronounced “ripple”)—is the de facto standard for IoT networks. However, it neglects to exploit IoT devices’ full capacity to optimize their transmission power, mainly because it is quite challenging to do so in parallel with the routing strategy, given the dynamic nature of wireless links ...
Iliar Rabet, Hossein Fotouhi, Mário Alves, Maryam Vahabi, Mats Björkman   +4 more
openaire   +3 more sources