Results 31 to 40 of about 616,195 (311)

Local Overexpression of Interleukin-11 in the Central Nervous System Limits Demyelination and Enhances Remyelination

Mediators of Inflammation, 2013
Demyelination is one of the pathological hallmarks of multiple sclerosis (MS). To date, no therapy is available which directly potentiates endogenous remyelination.
Anurag Maheshwari, Kris Janssens, Jeroen Bogie, Chris Van Den Haute, Tom Struys, Ivo Lambrichts, Veerle Baekelandt, Piet Stinissen, Jerome J. A. Hendriks, Helena Slaets, Niels Hellings   +10 more
doaj   +1 more source

Proper Methodology and Methods of Collecting and Analyzing Slavery Data: An Examination of the Global Slavery Index

Social Inclusion, 2014
The Global Slavery Index aims to, among other objectives, recognize the forms, size, and scope of slavery worldwide as well as the strengths and weaknesses of individual countries.
Andrew Guth, Robyn Anderson, Kasey Kinnard, Hang Tran   +3 more
doaj   +1 more source

Enchantment and critical distance in EU legal scholarship: what role for institutional lawyers?

European Law Open, 2022
The legal experts working for the European Union (EU) institutions facilitate EU policy-making activities. But no less importantly, they also shape the evolution of EU law.
Päivi Leino-Sandberg
doaj   +1 more source

Design Thinking-Driven Policy Imperatives for the Curricular Integration of PISA 2029’s MAIL Competency in Filipino In-Service Teacher Training

GiLE Journal of Skills Development
In the Philippine educational context, In-Service Teacher Training (INSET) remains central to teacher professional development and to sustaining educational reforms.
Marge Joseph Sardo, Roxan Villanueva, Christine Joy David, Pedro III Coronado, Marwin Obmerga   +4 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Crosstalk with Inflammatory Macrophages Shapes the Regulatory Properties of Multipotent Adult Progenitor Cells

Stem Cells International, 2017
Macrophages and microglia are key effector cells in immune-mediated neuroinflammatory disorders. Driving myeloid cells towards an anti-inflammatory, tissue repair-promoting phenotype is considered a promising strategy to halt neuroinflammation and ...
Stylianos Ravanidis, Jeroen F. J. Bogie, Raf Donders, Robert Deans, Jerome J. A. Hendriks, Piet Stinissen, Jef Pinxteren, Robert W. Mays, Niels Hellings   +8 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Transnational reflections on transnational research projects on men, boys and gender relations [PDF]

, 2015
This article reflects on the research project, ‘Engaging South African and Finnish youth towards new traditions of non-violence, equality and social well-being’, funded by the Finnish and South African national research councils, in the context of wider ...
Beck U., Cleaver F., Connell R., Connell R., Cornwall A., Edwards P., Esping-Andersen G., Esping-Andersen G., Gardner-Chloros P., Gibson-Graham J. K., Grewal I., Halley J., Hannerz U., Hearn J., Hearn J., Hearn J., Hearn J., Hearn J., Hearn J., Hearn J., Hirst P. Q., Hountondji P. J., Jones A., Lie J., Moberg E., Oleksy E., Parpart J. L., Petras J., Pringle K., Ruspini E., Sainsbury. D, Scott J. C., Silverman K, Steans J., van der Gaag N, Young B., Yuval-Davis N.   +36 more
core   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

From transnational to multinational education: emerging trends in international higher education [PDF]

, 2014
Transnational, or cross-border, education is attracting increasing interest, as universities extend their reach across borders to open up huge new markets.
Bordogna, C, Healey, N
core