Results 41 to 50 of about 53,258 (285)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Manifold Learning for Aerodynamic Shape Design Optimization
AerospaceThe significant computational cost incurred due to the iterative nature of Computational Fluid Dynamics (CFD) in traditional aerodynamic shape design frameworks poses a major challenge, especially in the context of modern integrated design requirements ...
Boda Zheng +3 more
doaj +1 more source
Vietnam Journal of Mechanics, 2011 For compressible flows, the transonic state depends on the geometry, Mach number and the incidence. This effect can produce shock wave. Some studies showed that the interaction between shock wave and boundary layer concerns separation phenomenon. Studies
Hoang Thi Bich Ngoc, Nguyen Manh Hung
doaj +1 more source
Numerical Study of the Lift Enhancement Mechanism of Circulation Control in Transonic Flow
Aerospace, 2021 The lift of an aircraft can be effectively enhanced by circulation control (CC) technology at subsonic speeds, but the efficiency at transonic speeds is greatly decreased. The underlying mechanism of this phenomenon is not fully understood. In this study,
Ye Chen +5 more
doaj +1 more source
Global Solutions of Viscous Transonic Flows in Kerr Geometry I: Weak Viscosity Limit [PDF]
, 1996 We present fully general relativistic equations governing viscous transonic flows in vertical equilibrium in Kerr geometry. We find the complete set of global solutions (both for Optically thick and optically thin flows) in the weak viscosity limit.
Chakrabarti, Sandip K.
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Sensitivity analysis and multi-objective robust design optimization of compact aero-engine nacelles
Engineering Applications of Computational Fluid MechanicsFuture civil aero-engines are expected to feature larger bypass ratios and fan diameters to reduce specific thrust and improve propulsive efficiency, thereby lowering specific fuel consumption. These new configurations introduce design challenges, as the
Guocheng Tao +6 more
doaj +1 more source
Receptivity and Stability Theory Analysis of a Transonic Swept Wing Experiment
Aerospace, 2023 Surface suction provides an efficient way to delay boundary layer transitions. In order to verify the suction effects and determine the mechanism of suction control in transonic swept wing boundary layers, wind tunnel transition measurements in a hybrid ...
Yuanqiang Liu +4 more
doaj +1 more source
Flow visualisation of a normal shock impinging over a rounded contour bump in a Mach 1.3 free-stream [PDF]
, 2016 An experimental study has been conducted to visualise the instantaneous streamwise and spanwise flow patterns of a normal shock wave impinging over a rounded contour bump in a Mach 1.3 free-stream.
Kontis, Konstantinos, Lo, Kin Hing
core +2 more sources