Results 41 to 50 of about 97,655 (378)
Taking a four-stage transonic compressor as the research object, the Lagrange particle tracking method was used to simulate the multiphase flow by considering the particle fragmentation, collision and evaporation models, and the influence of different ...
Shamiao Luo, Shaobin Li, Xizhen Song
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We have categorized possible transonic solutions of galactic outflows in the gravitational potential of DMH and SMBH using the isothermal, spherically symmetric and steady model.
Igarashi, Asuka+2 more
core +1 more source
The aerodynamic noise of an open rotor is one of the critical challenges that must be considered in its design and application. FODNOPP, a program specifically programmed to predict the aerodynamic discrete noise of single- and counter-rotating open ...
Hanyi Wang, Peng Shan, Yicheng Zhou
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The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi+5 more
wiley +1 more source
Noise Reduction of Open Cavities by Passive Flow Control Methods at Transonic Speeds using OpenFOAM
Flow over a cavity is one of the most intriguing problems in aeronautics. Although geometry is simple, the physics of cavity requires uttermost attention.
Oğuzhan DEMİR+2 more
doaj
On Transonic Marginal Separation [PDF]
AbstractLaminar boundary‐layer separation near the leading edge of a thin airfoil is one of the principal factors that limits the lift force acting on the airfoil. Marginal separation, in particular, denotes the onset of separation which is accompanied by the formation of a short separation bubble.
Alfred Kluwick, Bernhard Streibl
openaire +2 more sources
We investigated the seeded assembly of 0N3R tau and two variants, C322A and C322S, designed to model the mutation landscape at residue 322, using Alzheimer's disease brain homogenates in a real‐time quaking‐induced conversion (RT‐QuIC) assay. The C322A variant formed filaments that partially resembled the paired helical filament (PHF) structure ...
Alessia Santambrogio+9 more
wiley +1 more source
Manifold Learning for Aerodynamic Shape Design Optimization
The significant computational cost incurred due to the iterative nature of Computational Fluid Dynamics (CFD) in traditional aerodynamic shape design frameworks poses a major challenge, especially in the context of modern integrated design requirements ...
Boda Zheng+3 more
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For compressible flows, the transonic state depends on the geometry, Mach number and the incidence. This effect can produce shock wave. Some studies showed that the interaction between shock wave and boundary layer concerns separation phenomenon. Studies
Hoang Thi Bich Ngoc, Nguyen Manh Hung
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