Results 61 to 70 of about 50,445 (343)

Influences of the compressibility on aerodynamic characteristics of profile under the transonic flow theory

Vietnam Journal of Mechanics, 2007
Transonic flows are complex problems. At certain Mach numbers, in gas flows there are local transitions from the subsonic into the supersonic and reciprocally, especially the discontinuity throughout shock waves.
Hoang Thi Bich Ngoc
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Sensitivity analysis and multi-objective robust design optimization of compact aero-engine nacelles

Engineering Applications of Computational Fluid Mechanics
Future civil aero-engines are expected to feature larger bypass ratios and fan diameters to reduce specific thrust and improve propulsive efficiency, thereby lowering specific fuel consumption. These new configurations introduce design challenges, as the
Guocheng Tao, Yang Liu, Zhouteng Ye, Chengwei Fan, Yanzhao Gong, Yan Yan, Jiahuan Cui   +6 more
doaj   +1 more source

Calculation of transonic flows around profiles with blunt and angled leading edges

Vietnam Journal of Mechanics, 2016
Transonic flow is a mixed flow of subsonic and supersonic regions. Because of this mixture, the solution of transonic flow problems is obtained only when solving the differential equations of motion with special treatments for the transition from ...
Hoang Thi Bich Ngoc, Nguyen Manh Hung
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Numerical Investigation of Forced Response in a Transonic Compressor Stage—Highlighting Challenges Using Experimental Validation

International Journal of Turbomachinery, Propulsion and Power
An experiment-supported simulation process chain is set up to perform numerical forced response analyses on a transonic high-pressure compressor front stage at varying operating conditions.
Nicklas Kilian, Fabian Klausmann, Daniel Spieker, Heinz-Peter Schiffer, Mauricio Gutiérrez Salas   +4 more
doaj   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Influence of Transonic Flutter on the Conceptual Design of Next-Generation Transport Aircraft

AIAA Journal, 2018
Transonic aeroelasticity is an important consideration in the conceptual design of next-generation aircraft configurations.
Max M. J. Opgenoord, M. Drela, K. Willcox   +2 more
semanticscholar   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source