Results 31 to 40 of about 41,355 (316)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

A Modified Fifth-Order WENO-HLLC Riemann Solver for Transonic Viscous Flows around Helicopter Rotor in Hover

open access: yesShock and Vibration, 2022
This paper presents a modified fifth-order WENO-HLLC Riemann solver for the transonic compressible viscous flows around the helicopter rotor in hover. The HLLC approximate Riemann solver is proposed to discrete the convection term involving grid velocity
Li Xu, Fengfeng Zhao, Jingjing Cai
doaj   +1 more source

Integration of ejectors into high-speed aircraft [PDF]

open access: yes, 1979
The integration of ejectors into forebodies is considered for transonic and supersonic flight.
Duvvuri, T.
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Study of Separation Control of Vortex Generators on Transonic Wings

open access: yesJournal of Fluid Science and Technology, 2011
Flows around vortex generators (VGs), which serve as one of the important flow control methods, are investigated by solving Reynolds-Averaged Navier-Stokes (RANS) equations. The influences on the main flow of VGs are intended to explore.
Jingbo HUANG   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Accurate 2-D Modelling of Transonic Compressor Cascade Aerodynamics

open access: yesAerospace, 2019
Modern aeronautic fans are characterised by a transonic flow regime near the blade tip. Transonic cascades enable higher pressure ratios by a complex system of shockwaves arising across the blade passage, which has to be correctly reproduced in order to ...
Tommaso Piovesan   +2 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

On the challenge of five-hole-probe measurements at high subsonic Mach numbers in the wake of transonic turbine cascades

open access: yesJournal of the Global Power and Propulsion Society, 2018
Five-hole-probes are common use in turbomachinery flow investigations, even though, inserting a probe into a flow field inevitably induces perturbations to the flow which can falsify the measurement results, especially when exposed to transonic flows ...
Marcel Boerner   +2 more
doaj   +1 more source

Flow Characteristics and Loss Models of the Transonic Radial Turbine

open access: yesApplied Sciences, 2022
A hydrogen turbo hybrid power system has the significant advantages of zero carbon emissions, high efficiency and high reliability. The need to increase the power density of hydrogen turbo hybrid power systems and improve the adaptability of turbines ...
Cheng Zhu, Weilin Zhuge, Yangjun Zhang
doaj   +1 more source

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