Results 111 to 120 of about 22,527 (307)

Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features

Advanced Healthcare Materials, EarlyView.
ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato, Hanan Abumanhal‐Masarweh, Martí de Cabo, Pablo Guerra, Marilena Hadjidemetriou, Neus Lozano, Kostas Kostarelos   +6 more
wiley   +1 more source

Development of a multiple-parameter nonlinear perturbation procedure for transonic turbomachinery flows: Preliminary application to design/optimization problems [PDF]

An investigation was conducted to continue the development of perturbation procedures and associated computational codes for rapidly determining approximations to nonlinear flow solutions, with the purpose of establishing a method for minimizing ...
Elliott, J. P., Spreiter, J. R., Stahara, S. S.   +2 more
core   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

TRANSONIC FLOWS, SHOCK WAVE — TURBULENT BOUNDARY LAYER INTERACTION

TASK Quarterly, 1998
Shock wave - boundary layer interaction is one of the most important phenomenon in transonic flows. Due to its complexity it is difficult as well for experimental as for numerical study.
PIOTR DOERFFER, JAROSŁAW KACZYŃSKI
doaj  

An LU implicity scheme for high speed inlet analysis [PDF]

A numerical method is developed to analyze the inviscid flowfield of a high speed inlet by the solution of the Euler equations. The lower-upper implicit scheme in conjunction with adaptive dissipation proves to be an efficient and robust nonoscillatory ...
Jameson, A., Yoon, S.
core   +1 more source

Local measurements in turbulent flows through cross correlation of optical signals [PDF]

, 1967
Crossed beam correlation method measures turbulent fluctuations in transonic and supersonic flows. Two collimated beams of radiation are crossed at the point of interest in the flow, and the power loss of each beam is measured with two independent ...
Fisher, M. J.
core   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Aerodynamic flow analysis using conditional convolutional autoencoder in various flow conditions and application to CFD-based design optimization

Advances in Aerodynamics
This study investigates the accuracy and efficiency of a convolutional autoencoder in predicting flow solutions of diverse characteristics, including strong local nonlinearity and unsteady wake vortices.
Wontae Hwang, Donggun Lee, Junghun Shin, Kumwon Cho, Seongim Choi   +4 more
doaj   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Application of shock tubes to transonic airfoil testing at high Reynolds numbers [PDF]

Performance analysis of a gas-driven shock tube shows that transonic airfoil flows with chord Reynolds numbers of the order of 100 million can be produced, with limitations being imposed by the structural integrity of the facility or the model.
Chaney, M. J., Chapman, G. T., Cook, W. J., Presley, L. L.   +3 more
core   +1 more source