Results 61 to 70 of about 620,891 (356)

State capture through indemnification demands? Effects on equity in the global distribution of COVID-19 vaccines

open access: yesJournal of Pharmaceutical Policy and Practice, 2022
Background State capture by the pharmaceutical industry is a form of corruption whereby pharmaceutical companies shift laws or policies about their products away from the best interest of the public and toward their private benefit.
Ariel Gorodensky, Jillian C. Kohler
doaj   +1 more source

Transparency

open access: yes, 2018
In 2013, the G-20 asked the OECD to develop new rules for corporate tax transparency, pushed by civil society activists. World leaders had agreed that increased transparency was urgently needed to help shore up national fiscal systems and alleviate social injustices.
openaire   +3 more sources

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

Comparison of treatment effect sizes from pivotal and postapproval trials of novel therapeutics approved by the FDA based on surrogate markers of disease: a meta-epidemiological study

open access: yesBMC Medicine, 2018
Background The U.S. Food and Drug Administration (FDA) often approves new drugs based on trials that use surrogate markers for endpoints, which involve certain trade-offs and may risk making erroneous inferences about the medical product’s actual ...
Joshua D. Wallach   +6 more
doaj   +1 more source

On the Concept of Transparency: A Systematic Literature Review

open access: yesIEEE Access, 2022
Over a decade since transparency was introduced as a first-class concept in computing, transparency is still an emerging concept that is quite poorly understood.
Paulinus Ofem   +2 more
doaj   +1 more source

The Supply Chain Has No Clothes: Technology Adoption of Blockchain for Supply Chain Transparency

open access: yes, 2018
Blockchain technology, popularized by Bitcoin cryptocurrency, is characterized as an open-source, decentralized, distributed database for storing transaction information.
Kristoffer Francisco, David Swanson
semanticscholar   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li   +10 more
wiley   +1 more source

CURBING LAND CORRUPTION AN AFRICAN PREREQUISITE FOR FREE TRADE

open access: yesAfrican Journal on Land Policy and Geospatial Sciences
The existence, survival and continuity of a number of income-generating activities (farming, mining, etc.) depend on land, making it an important lever for a country's development.
Lovaniaina Mirella RANDRIAMALALA
doaj   +1 more source

Lived and care experiences of chronic musculoskeletal shoulder pain in Australian adults: A qualitative study

open access: yesArthritis Care &Research, Accepted Article.
Objectives Australian evidence on lived and care experiences of chronic musculoskeletal shoulder pain (CMSP), irrespective of disorder classification or disease, is limited. However, such evidence is important for person‐centred care and informing local service pathways and care guidelines or standards.
Sonia Ranelli   +8 more
wiley   +1 more source

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