Results 71 to 80 of about 801,450 (312)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Corupția, între blamare și alegere rațională

open access: yesSociologie Românească, 2005
This paper is meant to argue on the idea that petty corruption has a cultural support amongst the Romanian public. On the contrary, we sustain, Romania face some of it's paradoxes, as some nation-wide polls would show: (1) The most trusted public actors ...
Radu Mălureanu
doaj  

Clinical trial transparency at McGill University

open access: yesMcGill Journal of Medicine, 2020
Transparency in clinical trials is an issue under considerable scrutiny at present, and rightfully so, given that people's lives are both used as a resource in such research and affected by its results.
Richeek Pradhan, Olivia Bonardi
doaj  

Systematic overview of Freedom of Information Act requests to the Department of Health and Human Services from 2008 to 2017

open access: yesResearch Integrity and Peer Review, 2019
Background The Freedom of Information Act (FOIA) provides access to unreleased government records that can be used to enhance the transparency and integrity of biomedical research. We characterized FOIA requests to Department of Health and Human Services
Alexander C. Egilman   +4 more
doaj   +1 more source

Leaving no one behind: Party clientelism in social welfare in Serbia [PDF]

open access: yesAnali Pravnog Fakulteta u Beogradu
This article analyzes the functioning of party patronage and clientelism in the centers for social work. Building on previous research, based on qualitative research conducted in 2023 in Serbia, we examine parasitic relations of informal and formal ...
Vuković Danilo, Stefanović Marija
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Transparency Under Scrutiny: Information Disclosure in Global Environmental Governance [PDF]

open access: yes, 2008
Although transparency is a key concept of our times, it remains a relatively understudied phenomenon in global environmental politics. The link between transparency and accountable, legitimate and effective governance is assumed, yet the nature and ...
Aarti Gupta, Gupta, A.
core   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Global Contract-level Public Procurement Dataset

open access: yesData in Brief
One-third of total government spending across the globe goes to public procurement, amounting to about 10 trillion dollars a year. Despite its vast size and crucial importance for economic and political developments, there is a lack of globally ...
Mihály Fazekas   +3 more
doaj   +1 more source

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