Results 61 to 70 of about 24,248 (166)

A cryogenic liquid-mirror telescope on the moon to study the early universe

, 2008
We have studied the feasibility and scientific potential of zenith observing liquid mirror telescopes having 20 to 100 m diameters located on the moon.
Angel R., Bernard Foing, Daniel J. Eisenstein, Ermanno F. Borra, Gardner J. P., Jean‐Luc Josset, Ki Bui Ma, McCoy J. E., McCoy J. E., Omar Seddiki, Paul Hickson, Paul van Susante, Pelizzari M. A., Roger Angel, Simon P. Worden, Simon Thibault, Stubbs T. J., Suresh Sivanandam   +17 more
core   +1 more source

Differential segment‐specific signalling pathways for guanylate cyclase C‐activated anion secretion in murine ileocolon

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu, Johannes Reiner, Franz Hofmann, Azam Salari, Ursula Seidler   +4 more
wiley   +1 more source

Rotor systems research aircraft predesign study. Volume 4: Preliminary draft detail specification [PDF]

The RSRA requirements are presented in a detail specification format. Coverage of the requirements includes the following headings: (1) aircraft characteristics, (2) general features of design and construction, (3) aerodynamics, (4) structural design ...
Linden, A. W., Miller, A. N.
core   +1 more source

Index to nasa tech briefs, issue number 2 [PDF]

, 1965
Annotated bibliography on technological innovations in NASA space ...

core   +1 more source

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

Cell Proliferation, EarlyView.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang, Jinrui Li, Xingjia Mao, Wanyu Wang, Yansong Li, Xuefei Hu, Jinjie Zhong, Fengdong Zhao, Linlin Wang   +8 more
wiley   +1 more source

Genetic dissection reveals distinct contributions of the eS31 N‐terminal domain to translational accuracy in Saccharomyces cerevisiae

The FEBS Journal, EarlyView.
The eukaryote‐specific N‐terminal domain (NTD) of eS31 uses two distinct strategies to maintain translation fidelity. During elongation, a positively charged “hotspot” fine‐tunes the selection of incoming aa‐tRNA. During termination, the entire NTD acts as a structural scaffold to ensure the correct positioning of the release factor eRF1.
Qingxuan Gao, Hiroshi Otsuka, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Electronic Components Subsystems and Equipment: a Compilation [PDF]

Developments in electronic components, subsystems, and equipment are summarized. Topics discussed include integrated circuit components and techniques, circuit components and techniques, and cables and ...

core   +1 more source

Pointing control for the SPIDER balloon-borne telescope

, 2014
We present the technology and control methods developed for the pointing system of the SPIDER experiment. SPIDER is a balloon-borne polarimeter designed to detect the imprint of primordial gravitational waves in the polarization of the Cosmic Microwave ...
Ade, Peter A. R., Amiri, Mandana, Benton, Steven J., Bock, Jamie J., Bond, J. Richard, Bryan, Sean A., Chiang, H. Cynthia, Contaldi, Carlo R., Crill, Brendan P., Doré, Olivier P., Farhang, Marzieh, Filippini, Jeffrey P., Fissel, Laura M., Fraisse, Aurelien A., Gambrel, Anne E., Gandilo, Natalie N., Golwala, Sunil R., Gudmundsson, Jon E., Halpern, Mark, Hasselfield, Matthew, Hilton, Gene C., Holmes, Warren A., Hristov, Viktor V., Irwin, Kent D., Jones, William C., Kermish, Zigmund D., Kuo, Chao-Lin, MacTavish, Carolyn J., Mason, Peter V., Megerian, Krikor G., Moncelsi, Lorenzo, Morford, Tracy A., Nagy, Johanna M., Netterfield, C. Barth, O'Brient, Roger, Rahlin, Alexandra S., Reintsema, Carl D., Ruhl, John E., Runyan, Marcus C., Shariff, Jamil A., Soler, Juan D., Trangsrud, Amy, Tucker, Carole E., Tucker, Rebecca S., Turner, Anthony D., Weber, Alexis C., Wiebe, Donald V., Young, Edward Y.   +47 more
core   +1 more source

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

Journal of Integrative Plant Biology, EarlyView.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia, Medha Noopur, Ishana Bhattacharya, Bhaskar Chandra Sahoo, Mritunjay Kasera, Naga Jyothi Pullagurla, Smritikana Dutta, Guizhen Liu, Gabriel Schaaf, Henning Jessen, Debabrata Laha, Souvik Bhattacharjee, Saikat Bhattacharjee   +12 more
wiley   +1 more source

The parameters and measurements of the destabilizing actions of rotating machines, and the assumptions of the 1950's [PDF]

The measurability of destabilizing actions is demonstrated for a rotor built to produce a forward circular, self excited malfunction (gas whip). It is argued that the continued use of past modeling technqiues is unfortunate in that it has led to the use ...
Bently, D. E.
core   +1 more source