Results 151 to 160 of about 1,198,227 (290)
Progress of non‐motor symptoms in early‐onset Parkinson's disease
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang+5 more
wiley +1 more source
Berberine protects against lung injury induced by liver transplantation through upregulating PPARγ and suppressing NF-κB-mediated pyroptosis pathway. [PDF]
Liu W, Liang X, Huo M, Wang Y, Zhang G.
europepmc +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar+2 more
wiley +1 more source
Safety and long-term efficacy of autologous hematopoietic cell transplantation for patients with systemic sclerosis. [PDF]
Gavriilaki E+15 more
europepmc +1 more source
Diagnosis and management of gestational trophoblastic disease: 2025 update
Abstract Gestational trophoblastic disease (GTD) arises from abnormal placenta and comprises a spectrum of premalignant to malignant disorders. Changes in the epidemiology of GTD have been noted in various countries. In addition to histology, molecular genetic studies can help in the diagnostic pathway.
Hextan Y. S. Ngan+7 more
wiley +1 more source
Transplant-Associated Thrombotic Microangiopathy After Autologous Hematopoietic Stem Cell Transplantation Treated With Eculizumab. [PDF]
Tokura T+4 more
europepmc +1 more source
This study proposes an innovative therapeutic approach by combining RRM2 gene knockout with a nanocarrier system, significantly enhancing the efficacy of radiofrequency ablation for hepatocellular carcinoma. The study developed a tumor microenvironment‐responsive nanosystem that achieves synergistic effects through SPIO‐mediated and RRM2 knockout ...
Weiliang Hou+19 more
wiley +1 more source
New insights into applications of base editor in hereditary disorders
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai+8 more
wiley +1 more source