Although the ribs are the only human bones capable of regenerating large‐scale defects, this remarkable ability declines with skeletal maturity and age. Here, we reproduce skeletal maturity and age‐related phenotypic changes in a mouse model of rib resection.
Luciana Yamamoto de Almeida+15 more
wiley +1 more source
Stem cell-derived pancreatic beta cells: a step closer to functional diabetes treatment? [PDF]
Ogieuhi IJ+13 more
europepmc +1 more source
ABSTRACT The basophil activation test (BAT) is gaining increasing relevance as an ex vivo functional assay in allergy to evaluate IgE‐mediated hypersensitivity reactions to food allergens, venoms, and drugs and to monitor tolerance induction. Establishing universal standard operating protocols has been difficult, due to several challenges including ...
Mariona Pascal+18 more
wiley +1 more source
Efficacy evaluation of autologous muscle flap transposition or myocutaneous flap transplantation for postoperative chronic empyema with bronchopleural fistula. [PDF]
Wang L+6 more
europepmc +1 more source
The use of deidentified organ donor testes for research
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova+4 more
wiley +1 more source
Pharmacokinetics and outcome of high-dose melphalan followed by autologous stem cell transplantation in dialysis-dependent patients with multiple myeloma. [PDF]
Mecklenbrauck R+6 more
europepmc +1 more source
Corrigendum: Advancements in autologous peripheral nerve transplantation care: a review of strategies and practices to facilitate recovery. [PDF]
Xu G+10 more
europepmc +1 more source
Simultaneous Ex Situ Normothermic Perfusion of Paired Kidneys in Pigs
This pig model of simultaneous perfusion of paired kidneys in normothermia suggests that intra‐individual variation is relatively low, enabling one kidney to be employed as a reliable comparator of the other kidney for assessing treatments before kidney transplantation.
Margaux Navez+12 more
wiley +1 more source
Stem cell treatments for female reproductive disorders: a comprehensive review. [PDF]
Nair R+4 more
europepmc +1 more source
The Aetiology of Elevated Total Serum Immunoglobulin E in Children
ABSTRACT Aim The paucity of real‐world data on the aetiology of elevated total serum immunoglobulin E (TS‐IgE) in children afflicts families and health care systems with diagnostic uncertainty. We explored a cohort of children with TS‐IgE levels over 1000 kU/L, focusing on the prevalence of atopic and non‐atopic conditions, the aetiology of extremely ...
Aliisa Ärölä+2 more
wiley +1 more source