Results 81 to 90 of about 166,647 (243)

A Preliminary Study on the Therapeutic Role of γδT Cells in Triple‐Negative Breast Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study was aimed to elucidate the cytotoxic effects of γδT cells on triple‐negative breast cancer (TNBC) cells and assess their antitumor efficacy in a mouse xenograft model. Furthermore, the underlying mechanisms of γδT cell action on TNBC were explored.
Shi Qiu, Qin‐Yu Han, Xian Zhao, Wen‐Jing Li, Xiang‐Qi Li   +4 more
wiley   +1 more source

Generation of Oligodendrocyte Progenitor Cells From Mouse Bone Marrow Cells. [PDF]

, 2019
Oligodendrocyte progenitor cells (OPCs) are a subtype of glial cells responsible for myelin regeneration. Oligodendrocytes (OLGs) originate from OPCs and are the myelinating cells in the central nervous system (CNS).
Casella, Giacomo, Han, Juan-Juan, Jia, Ling-Yu, Li, Xing, Lu, Xin-Yu, Rostami, A. M., Tian, Jing, Yang, Ting, Ye, Ze-Qing, Zhang, Yuan   +9 more
core   +1 more source

Autologous chondrocyte implantation, matrix‐induced autologous chondrocyte implantation, osteochondral autograft transplantation and osteochondral allograft improve knee function and pain with considerations for patient and cartilage defects characteristics: A systematic review and meta‐analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Previous studies have reported on the outcomes of autologous chondrocyte implantation (ACI) versus matrix‐induced ACI (MACI) and microfracture. Specific clinical outcomes of ACI, MACI, osteochondral autograft transplantation (OAT) and osteochondral allograft (OCA) have not been well studied.
Joseph E. Nassar, Grace Guerin, Taidhgin Keel, Raffaella Russo, Filippo Familiari, Luke V. Tollefson, Robert F. LaPrade   +6 more
wiley   +1 more source

Matrix‐assisted autologous chondrocyte transplantation is effective at mid/long‐term for knee lesions: A systematic review and meta‐analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This systematic review with meta‐analysis evaluates the long‐term efficacy of matrix‐assisted autologous chondrocyte transplantation (MACT) in terms of functional scores using scaffolds made of hyaluronic acid (HA) or collagen (C). Methods Nineteen articles met the eligibility criteria for the analysis.
Alessandra Colombini, Vincenzo Raffo, Silvia Gianola, Greta Castellini, Giuseppe Filardo, Silvia Lopa, Matteo Moretti, Laura de Girolamo   +7 more
wiley   +1 more source

Autologous bone grafting combined with spheroid‐based matrix‐induced autologous chondrocyte implantation for osteochondral defects of the knee: Good clinical outcomes alongside abnormal postoperative gait patterns

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate the clinical and functional outcomes of autologous bone grafting with spheroid‐based matrix‐induced autologous chondrocyte implantation (MABCI) for osteochondral defects of the knee by analysing pre‐ and postoperative patient‐reported outcome measures (PROMs).
Stephan Oehme, Danko Dan Milinkovic, Azzurra Paolucci, Sophie Krafzick, Stephen Fahy, Philipp Damm, Tobias Winkler, Tobias Jung, Benjamin Bartek   +8 more
wiley   +1 more source

Post‐operative joint stiffness after Bereiter trochleoplasty does not affect 2‐year improvement in patient‐reported outcomes. A prospective cohort study of 374 Bereiter trochleoplasties

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Bereiter trochleoplasty (TP) is a well‐described procedure to address trochlear dysplasia (TD). Post‐operative joint stiffness with reduced range of motion (ROM) is a common complication usually requiring arthroscopically assisted manipulation (AAM) with the removal of adhesions and scar tissue. Inferior clinical outcomes after TP have
Christian Dippmann, Christos Soleas, Anke Simone Rechter, Volkert Siersma, Kristoffer Weisskirchner Barfod, Peter Lavard   +5 more
wiley   +1 more source

Very low dislocation rate and good clinical outcome after Bereiter trochleoplasty and additional procedures following the Copenhagen patella–femoral instability algorithm: One‐ and two‐years outcomes from a consecutive cohort of 368 cases

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Patello–femoral instability (PFI) is often caused by predisposing factors, with trochlea dysplasia (TD) as the most prominent. Untreated patellar instability leads to impaired function and an increased risk of patellofemoral osteoarthritis.
Christian Dippmann, Volkert Siersma, Simone Rechter, Kristoffer W. Barfod, Peter Lavard   +4 more
wiley   +1 more source

Isolated central nervous system relapse in mantle cell lymphoma

eJHaem, EarlyView.
Radu Chiriac, Zofia Gross
wiley   +1 more source

Treatment of large chondral lesions with an autologous minced cartilage technique and synovial flap leads to superior results compared to matrix associated autologous chondrocyte transplantation technique after 24 months: A controlled clinical trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Treating large cartilage lesions in the knee remains a challenge. While matrix‐associated autologous chondrocyte implantation (MACI) is the gold standard for medium to large lesions, the minced cartilage technique has shown promise in smaller defects. Enhancing this technique with biomaterials has been suggested for larger lesions, but
Johanna Mayr, Franziska Warth, Nicola Oehler, Martin Majewski, Christoph Lutter, Fabian Blanke   +5 more
wiley   +1 more source

Breaking Boundaries: Chronic Diseases and the Frontiers of Immune Microenvironments

Med Research, EarlyView.
ABSTRACT The immune microenvironment includes immune cells, cytokines, extracellular matrix, vesicles, etc. The interactions between these components form a unique local immune microecology. Although immunity serves as the defense against external pathogens, aberrant immune activation often contributes to disease development.
Guoqing Li, Yuxuan Wan, Alan Jiao, Ke Jiang, Gaoyuan Cui, Jinxin Tang, Simin Yu, Zhengang Hu, Songfeng Zhao, Zhenjie Yi, Lifu Long, Yang Yang, Xuehao Cui, Chunrun Qu   +13 more
wiley   +1 more source