Results 21 to 30 of about 77,491 (296)

Dendritic Cells Transfected with MHC Antigenic Determinants of CBA Mice Induce Antigen-Specific Tolerance in C57Bl/6 Mice

Journal of Immunology Research, 2020
Background. Nonspecific immunosuppressive therapy for graft rejection and graft-versus-host disease (GVHD) is often accompanied by severe side effects such as opportunistic infections and cancers.
Sergey V. Sennikov, Valeriy P. Tereshchenko, Vasiliy V. Kurilin, Julia A. Shevchenko, Julia A. Lopatnikova, Alexander N. Silkov, Amir Z. Maksyutov, Maria S. Kuznetsova, Nadezda Y. Knauer, Aleksey S. Bulygin, Julia N. Khantakova   +10 more
doaj   +1 more source

HOMOLOGOUS TRANSPLANTATION OF BOVINE ETHMOID CARCINOMA CELLS [PDF]

Journal of Veterinary and Animal Sciences, 2008
A study was undertaken to transplantV bovine ethmoid tumour cells into calves immunosuppressed with hydrocortisone. Twelve calves were equally grouped into two groups of control and immunosuppressed group.
Ajith Jacob George, K. M. Ramachandran, A. Rajan, K. T. Punnoose, C. B. Manomohan   +4 more
doaj  

Acquired cystic kidney disease in allograft with long-standing poor function

Brazilian Journal of Nephrology
Acquired Cystic Kidney Disease (ACKD) is regarded as a common late condition of end stage renal damage and expresses its most important features when associated with long term hemodialysis. ACKD is also widely known as a premalignant lesion.
Leonardo Cardili, Henrique Machado de Sousa Proença, Marcello Fabiano de Franco   +2 more
doaj   +1 more source

Experimental model for composite tissue allotransplantations Modelo experimental para alotransplantes de tecido composto

Acta Cirúrgica Brasileira, 2004
In homologous transplantation or allotranplantation of limbs, the great tissue diversity causes variability in the rejection process and, consequently, its immunology is very complex.
Lydia Masako Ferreira, Luiz Roberto Kobuti Ferreira   +1 more
doaj   +1 more source

Tissue culture of human thyroid cancer [PDF]

, 1968
Human thyroid cancer cells in the pleural effusion were serially cultivated in vitro. Three kinds of cell lines were established from the same primary culture and were designated as PS, TS and TR lines, respectively.
Hirose, Masaharu
core   +1 more source

Reconstitution of ovarian function following transplantation of primordial germ cells

Scientific Reports, 2017
Ovarian aging occurs earlier than somatic aging. We tested the hypothesis that ovarian functions could be artificially reconstructed by transplantation of primordial germ cells (PGCs).
Ming Zeng, Xiaoyan Sheng, David L. Keefe, Lin Liu   +3 more
doaj   +1 more source

A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X. [PDF]

, 2008
BackgroundActivated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is
Arruda, VR, Chu, K, Golden, JA, Herzog, RW, High, KA, Labosky, PA, Margaritis, P, Tai, SJ   +7 more
core   +2 more sources

Cases report and diagnosis and treatment of passenger lymphocyte syndrome after liver and renal transplantation

Zhongguo shuxue zazhi
Objective To summarize the clinical features, serological features, blood transfusion protocols and treatment of 3 cases of passenger lymphocyte syndrome(PLS) after ABO-incompatibility liver and renal transplantation in our hospital, in order to provide ...
Yuxin HE, Yiran MA, Shuang ZHANG, Jingchun JIN   +3 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source