Results 31 to 40 of about 76,294 (297)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Impact of stem cell source on allogeneic stem cell transplantation outcome in hematological malignancies [PDF]

Vojnosanitetski Pregled, 2011
Background/Aim. Peripheral blood (PB) is used more frequently as a source of stem cells (SCs) for allogeneic transplantation. However, the influence of cell source on the clinical outcome of SC transplantation is not yet well established.
Stamatović Dragana, Balint Bela, Tukić Ljiljana, Elez Marija, Tarabar Olivera, Todorović Milena, Ostojić Gordana, Tatomirović Zeljka, Ljubenov Marika, Marjanović Slobodan, Malešević Milomir   +10 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

O uso de enxerto homólogo na revisão de artroplastias do quadril com cimentação do componente acetabular Use of homologous graft in hip arthroplasty reviews with acetabular component cementation

Acta Ortopédica Brasileira, 2006
A artroplastia total do quadril representa um grande avanço no tratamento das enfermidades ortopédicas que acometem o quadril. A soltura asséptica desta prótese pode causar lesões e perdas ósseas, representando um grande desafio para a reconstrução ...
Fábio Stuchi Devito, Rudelli Sergio Andrea Aristides, Emerson Kiyoshi Honda, Alceu Gomes Chueire   +3 more
doaj   +1 more source

Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth Decreases Cognitive Impairment from Chronic Cerebral Ischemia by Reducing Neuronal Apoptosis in Rats

Stem Cells International, 2020
Stem cells from human exfoliated deciduous teeth (SHED) are a unique postnatal stem cell population with high self-renewal ability that originates from the cranial neural crest.
Shu Zhu, Dongyu Min, Jianhong Zeng, Yetao Ju, Yao Liu, Xu Chen   +5 more
doaj   +1 more source

PHENOMENON OF DEMIKHOV. In the Sklifosovsky Institute (1960–1986). Demijоv V.P. Transplante experimental de órganos vitales. Madrid: Editorial Atlante, 1967

Трансплантология (Москва), 2021
For the first time, the article introduces into scientific circulation and analyzes the Preface by V.P. Demikhov to his book "Transplantation of vital organs in experiment", published in 1967 in Spanish under the title "Transplante experimental de ...
S. P. Glyantsev, Yu. G. Shatunova, A. Werner   +2 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Long-term patency and complications of ringed polytetrafluoroethylene grafts used for middle hepatic vein reconstruction in living-donor liver transplantation

Korean Journal of Transplantation, 2020
Background : Homologous vein allografts are adequate for reconstruction of the middle hepatic vein (MHV) in living-donor liver transplantation (LDLT). However, supply is a matter of concern. To replace homologous vein allografts, polytetrafluoroethylene (
I-Ji Jung, Shin Hwang, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Chul-Soo Ahn, Deok-Bog Moon, Ki-Hun Kim, Gil-Chun Park, Young-In Yoon, Yo-Han Park, Hui-Dong Cho, Jae-Hyun Kwon, Yong-Kyu Chung, Sang-Hyun Kang, Sung-Gyu Lee   +15 more
doaj   +1 more source

Bioinspired Design of a Wet‐Adhesive Cornea Glue Based on Recombinant Human Protein Networks

Advanced Functional Materials, EarlyView.
Natures protein‐based high performance materials e.g. elastin, silk and muscle proteins have been mimicked by a new protein‐hybrid material based on redesigned human partial sequences only, showing high wet‐adhesiveness and elasticity for biomedical applications.
Anna Resch, Matthias C. Huber, Alexander Resch, Andreas Schreiber, Thabo Lapp, Jan Dittrich, Frederic Eisen, Austin Julian Michalec, Viktoria Planz, Adrianna Kolberg, Mathaeus Tschaikowsky, Daniel Böhringer, Maike Windbergs, Thomas Reinhard, Bernd Rolauffs, Bizan N. Balzer, Günther Schlunck, Stefan M. Schiller   +17 more
wiley   +1 more source

Intra-abdominal Homologous Heart Transplantation

Experimental Biology and Medicine, 1969
SummaryA technique of homologous heart transplantation is described which permits study of the multiple aspects of cardiac function and rejection. Some preliminary results are described. Further utilization of this study model is indicated.
W A, Reed, I K, Crosby
openaire   +2 more sources