Results 71 to 80 of about 42,814 (266)

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Role of PINCH and Its Partner Tumor Suppressor Rsu-1 in Regulating Liver Size and Tumorigenesis [PDF]

, 2013
Particularly interesting new cysteine-histidine-rich protein (PINCH) protein is part of the ternary complex known as the IPP (integrin linked kinase (ILK)-PINCH-Parvin-α) complex.
Bhave, VS, Haynes, MM, Donthamsetty, Shashikiran, George K Michalopoulos, Shashikiran Donthamsetty, Meagan M Haynes, Mars, WM, Orr, A, Haynes, Meagan M., Bowen, WC, Anne Orr, Chuanyue Wu, Wu, Chuanyue, Orr, Anne, William C Bowen, Wu, C, Singh, Shree Ram, Vishakha S Bhave, Wendy M Mars, Bhave, Vishakha S., Michalopoulos, George K., Bhave, Vishakha, Donthamsetty, S, Mars, Wendy M., Michalopoulos, GK, Bowen, William C.   +25 more
core   +1 more source

Deciphering Intricacies in Directional CO2 Conversion From Electrolysis to CO2 Batteries

Advanced Energy Materials, EarlyView.
This review will delve into the inherent connections and distinctions of CO2‐directed conversion in ECO2RR and CO2 batteries, in terms of product types, catalyst selection, catalytic mechanisms, and electrochemical performances, while proposing a benchmarking framework for the evaluation of CO2 batteries and innovative CO2 battery configurations for ...
Changfan Xu, Huaping Zhao, Lizhuang Chen, Weidong Shi, Guosheng Shao, Yong Lei   +5 more
wiley   +1 more source

Reconstitution of ovarian function following transplantation of primordial germ cells

, 2017
Ovarian aging occurs earlier than somatic aging. We tested the hypothesis that ovarian functions could be artificially reconstructed by transplantation of primordial germ cells (PGCs).
Ming Zeng, David L. Keefe, Xiaoyan Sheng, Lin Liu   +3 more
core   +1 more source

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

Evolution and expression of the transplantation antigen gene family [PDF]

, 1985
Widera, Georg, Flavell, Richard A., Fahrner, Karen, Sherman, David, Devlin, James J., Mellor, Andrew L., Weiss, Elisabeth H.   +6 more
core   +1 more source

STUDIES IN THE TRANSPLANTATION OF BONE, V. The Capacity of Fresh and Treated Homografts of Bone to Evoke Transplantation Immunity

, 1963
1. Experiments to examine the antigenicity of homologous bone tissues in rats are reported. The tissues studied included fresh marrow-free cortical bone blocks and chips, fresh, boiled, frozen and freeze-dried marrow-containing iliac bone, fresh iliac ...
R. Geoffrey Burwell
core   +1 more source

The Homozygous p.(Arg215Ter) Variant in XRCC2 Is Associated With Atypical Fanconi Anemia Without Major Hematological Abnormalities in Childhood

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Fanconi Anemia (FA) is the most frequent inherited bone marrow failure syndrome. A role for the XRCC2 gene in FA was suspected in 2012 and confirmed in 2016, but only two affected individuals have been described thus far, and no long‐term follow‐up is available.
Sabina Cenciarelli, Giulia Bruna Marchetti, Maria Iascone, Maria Grazia Patricelli, Sara Giangiobbe, Gabriella Cinzia Pozzobon, Miriam Nella Savini, Fabio Giglio, Alessandro Aiuti, Paola Carrera, Francesca Ferrua, Angela Peron   +11 more
wiley   +1 more source

Development of homologous skin, bone and other soft tissues transplantation in Slovenia

, 2017
Transplantacija tkiva kao što su koža i kosti uspješno je pratila globalne trendove kroz povijest u Sloveniji. Prvi dokumentirani homologni kožni presadak spominje se već 1901.
Zvonka Zupanič Slavec, Zupanič Slavec, Zvonka, Matija Šatej, Šatej, Matija   +3 more
core  

Descemet's membrane as membranous support in RPE/IPE transplantation

, 1997
The correct orientation of retinal pigment epithelium (RPE) cells is necessary for the integrity and proper function of the retina. For transplantation of RPE/iris pigment epithelium (IPE) grafts to the subretinal space in age-related macular ...
Bartz-Schmidt, K U, Heimann, K, Schraermeyer, U, Thumann, Gabriele   +3 more
core   +1 more source