Results 41 to 50 of about 1,899,797 (360)
MEDIMP: 3D Medical Images with clinical Prompts from limited tabular data for renal transplantation [PDF]
arXiv, 2023 Renal transplantation emerges as the most effective solution for end-stage renal disease. Occurring from complex causes, a substantial risk of transplant chronic dysfunction persists and may lead to graft loss. Medical imaging plays a substantial role in renal transplant monitoring in clinical practice. However, graft supervision is multi-disciplinary,
arxiv
An Analysis of Early Renal Transplant Protocol Biopsies - the High Incidence of Subclinical Tubulitis [PDF]
, 2001 To investigate the possibility that we have been underestimating the true incidence of acute rejection, we began to perform protocol biopsies after kidney transplantation. This analysis looks at the one-week biopsies. Between March 1 and October 1, 1999,
Burdick +16 more
core +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Predicting Dosage of Immunosuppressant Drugs After Kidney Transplantation Using Machine Learning [PDF]
arXiv, 2023 While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage variance based on each patient's unique physiology, nephrologists face numerous difficulties when determining the precise
arxiv
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Revisiting Stem Cell-Based Clinical Trials for Ischemic Stroke
Frontiers in Aging Neuroscience, 2020 Stroke is the leading cause of serious long-term disability, significantly reducing mobility in almost half of the affected patients aged 65 years and older. There are currently no proven neurorestorative treatments for chronic stroke.
Joy Q. He +4 more
doaj +1 more source
Biomarkers in solid organ transplantation: establishing personalized transplantation medicine. [PDF]
, 2011 Technological advances in molecular and in silico research have enabled significant progress towards personalized transplantation medicine. It is now possible to conduct comprehensive biomarker development studies of transplant organ pathologies ...
Khatri, Purvesh +3 more
core +3 more sources
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Amniotic fluid-derived stem cells as an effective cell source for transplantation therapy in stroke
Brain Circulation, 2015 This review examines stem cells harvested from human amniotic fluid and considers their possible applications in regenerative medicine, specifically for stroke therapy.
Nicholas S Diaco +2 more
doaj +1 more source
IL-34 Actions on FOXP3+ Tregs and CD14+ Monocytes Control Human Graft Rejection
Frontiers in Immunology, 2020 Cytokines are major players regulating immune responses toward inflammatory and tolerogenic results. In organ and bone marrow transplantation, new reagents are needed to inhibit tissue destructive mechanisms and eventually induce immune tolerance without
Séverine Bézie +20 more
doaj +1 more source