Results 271 to 280 of about 18,682 (303)

Transplantation of Fetal Hematopoietic Stem Cells in Utero: The Creation of Hematopoietic Chimeras

Science, 1986
Transplantation of normal, immature, fetal hematopoietic cells into a preimmune fetal recipient with a congenital hemoglobinopathy may allow partial reconstitution of normal hemoglobin production without the complications associated with postnatal bone marrow transplantation (immunosuppression and the occurrence of graft versus host disease).
A W, Flake, M R, Harrison, N S, Adzick, E D, Zanjani   +3 more
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Production of ovine chimeras by inner cell mass transplantation.

Journal of animal science, 1987
Ovine chimeras were produced by micro-injection of isolated inner cell masses (ICM) into recipient blastocysts. Inner cell masses were isolated by immunosurgery. A total of 57 chimeric embryos was produced, 52 of which were transferred to recipient ewes. Thirty-seven live lambs were born, of which 15 were determined to be chimeric on the basis of blood
J E, Butler, G B, Anderson, R H, BonDurant, R L, Pashen, M C, Penedo   +4 more
openaire   +1 more source

Karyotype Analysis of Leukocytes of Gray Collie (Cyclic Neutropenia)-Normal Bone Marrow Transplant Chimeras Six Years After Transplantation

American Journal of Veterinary Research, 1980
SUMMARY Karyotype analysis was made on the leukocytes of 2 gray Collie (cyclic neutropenia)-normal bone marrow transplant chimeras transplanted 6 years previously to correct cyclic neutropenia of the gray Collie syndrome. In a male-to-female transplant chimera, all of the 50 metaphase spreads showed the karyotype of male donor origin.
D J, Matsas, T J, Yang
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Mixed Bone Marrow Chimeras as an Approach to Transplantation Tolerance

1987
Transplantation tolerance across a complete MHC barrier can be achieved in mice using lethal irradiation followed by reconstitution with a mixture of T-cell-depleted (TCD) syngeneic and allogeneic bone marrow cells.1,2 Such animals repopulate as stable mixed lymphohematopoietic chimeras, and enjoy improved survival compared with recipients of ...
Megan Sykes, Caroline H. Chester, David H. Sachs   +2 more
openaire   +1 more source

The Emerging Field of Human Neural Organoids, Transplants, and Chimeras

2021
Each year, tens of millions of individuals in the U.S. suffer from neurological and psychiatric disorders including neurodegenerative diseases such as Alzheimer's Disease and Parkinson's Disease, and psychiatric disorders such as autism spectrum disorder, depression and schizophrenia.
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Identification and Follow-up of Homologous and Heterologous Bone-marrow Transplants in Radiation-chimeras

International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1959
Using differences in the electrophoretic pattern between host and donor haemoglobins, the proliferation of grafted erythropoietic cells has been studied in irradiated mice treated with homologous bone marrow. The results have been compared with observations made after the transplantation of rat bone marrow into irradiated mice.
Welling, W., Vos, O., Weyzen, W.W.H., Bekkum, D.W. van   +3 more
openaire   +2 more sources

Production of sheep-goat chimeras by inner cell mass transplantation.

Journal of animal science, 1987
Embryos were surgically flushed from goats and sheep on d 6 and 7, respectively, following the first day of estrus (d 0). After enzymatic removal of the zonae pellucidae, inner cell masses were isolated from caprine blastocysts by immunosurgery. The intact inner cell masses were injected into ovine blastocysts with the aid of a micromanipulator. Twenty-
V J, Polzin, D L, Anderson, G B, Anderson, R H, BonDurant, J E, Butler, R L, Pashen, M C, Penedo, J D, Rowe   +7 more
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EFFECT OF THYMUS TRANSPLANTATION ON RADIATION CHIMERAS

Annals of the New York Academy of Sciences, 1964
Congdon, C C, Goodman, J W, Ferrebee, J W   +2 more
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A human chimera for von Willebrand disease following bone marrow transplantation.

The American journal of pediatric hematology/oncology, 1993
von Willebrand disease (vWD) is a common bleeding disorder characterized by quantitative or qualitative defects in von Willebrand factor (vWF), a protein important for coagulation and platelet adhesion. There are two forms of vWF currently recognized: plasma vWF synthesized by endothelial cells and platelet vWF produced within megakaryocytes.
R E, Ware, R I, Parker, L P, McKeown, M L, Graham   +3 more
openaire   +1 more source

Allogeneic unresponsiveness to orthotopic cardiac transplants in DL-A-identical radiation chimeras.

Transplantation proceedings, 1976
Nine Cooperstown beagles of known DL-A genotypes were exposed to supralethal total-body irradiation and received bone-marrow allografts from DL-A-identical donors. Four to 5 months later, the resulting chimeras received orthotopic cardiac allografts from their corresponding donors of marrow. Six chimeras died of operative complications in the immediate
A D, Boyd, F C, Spencer, H, Hirose, R M, Engelman, F D, Cannon, J W, Ferrebee, F T, Rapaport   +6 more
openaire   +1 more source