Results 31 to 40 of about 18,682 (303)

Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection

Cell Reports, 2019
Summary: Type I interferon (IFNα/β) pathways are fine-tuned to elicit antiviral protection while minimizing immunopathology; however, the initiating stimuli, target tissues, and underlying mechanisms are unclear.
Konrad C. Bradley, Katja Finsterbusch, Daniel Schnepf, Stefania Crotta, Miriam Llorian, Sophia Davidson, Serge Y. Fuchs, Peter Staeheli, Andreas Wack   +8 more
doaj   +1 more source

Reconstruction of Large Area of Deep Wound in the Foot and Ankle with Chimeric Anterolateral Thigh Perforator Flap

Orthopaedic Surgery, 2021
Objective To evaluate the clinical application and surgical efficacy of the chimeric perforator flap pedicled with the descending branch of the lateral circumflex femoral artery and the lateral thigh muscle flap for the reconstruction of the large area ...
Run‐guang Li, Can‐jun Zeng, Song Yuan, Ji‐jie Hu, Ping Zhang, Yun‐biao Chen, Shan‐wen Zhao, Gao‐hong Ren   +7 more
doaj   +1 more source

Graded potential of neural crest to form cornea, sensory neurons and cartilage along the rostrocaudal axis [PDF]

, 2004
Neural crest cells arising from different rostrocaudal axial levels form different sets of derivatives as diverse as ganglia, cartilage and cornea. These variations may be due to intrinsic properties of the cell populations, different environmental ...
Bronner-Fraser, Marianne, Conrad, Gary W., Lwigale, Peter Y.   +2 more
core   +2 more sources

Bone-marrow derived cells do not contribute to new beta-cells in the inflamed pancreas

Frontiers in Immunology, 2023
The contribution of bone-marrow derived cells (BMCs) to a newly formed beta-cell population in adults is controversial. Previous studies have only used models of bone marrow transplantation from sex-mismatched donors (or other models of genetic labeling)
Yinan Jiang, John Wiersch, Wei Wu, Wei Wu, Jieqi Qian, Jieqi Qian, Maharana Prathap R. Adama, Nannan Wu, Nannan Wu, Weixia Yang, Weixia Yang, Congde Chen, Congde Chen, Lingyan Zhu, Krishna Prasadan, George K. Gittes, Xiangwei Xiao   +16 more
doaj   +1 more source

Induction of donor-specific transplantation tolerance to skin and cardiac allografts using mixed chimerism in (A + B → A) in rats [PDF]

, 1993
Mixed allogeneic chimerism (A + B → A) was induced in rats by reconstitution of lethally irradiated LEW recipients with a mixture of T-cell depleted (TCD) syngeneic and TCD allogeneic ACI bone marrow. Thirty-seven percent of animals repopulated as stable
Cai, X, Fung, JJ, Markus, PM, Selvaggi, G, Starzl, TE   +4 more
core   +1 more source

Human-animal chimeras for autologous organ transplantation: technological advances and future perspectives [PDF]

Annals of Translational Medicine, 2019
Organ transplantation is the most promising curation for end-stage organ disease. However, the donor organ shortage has become a global problem that has limited the development of organ transplantation. Human-animal chimeras provide the ability to produce human organs in other species using autologous stem cells [e.g., induced pluripotent stem cells ...
Yingfei, Lu, Yu, Zhou, Rong, Ju, Jianquan, Chen   +3 more
openaire   +2 more sources

Immunomagnetic t-lymphocyte depletion (ITLD) of rat bone marrow using OX-19 monoclonal antibody [PDF]

, 1989
Graft versus host disease (GVHD) may be abrogated and host survival prolonged by in vitro depletion of T lymphocytes from bone marrow (BM) prior to allotransplantation. Using a mouse anti-rat pan T-lymphocyte monoclonal antibody (0×19) bound to monosized,
A. Pascualone, A.L. Hoffman, B.F. Banner, Barclay A, Berenson R J, Beschorner W E, Bril H, D.G. Sheahan, D.V. Cramer, Dallman M J, Elkins W L, Farnsworth A, Filipovich A H, Kvalheim G, L. Makowka, Lubaroff D M, Martin P J, Monchik G J, Oaks M K, P. Rettinger, Prentice H G, Reisner Y, Rodt H, Slavin R E, T.E. Starzl, Thtschka P J, Tsoi M-S, Van Bekkum D W, Vartdal F, Waldman H, X. Cai   +30 more
core   +1 more source

Dechorionation of Medaka Embryos and Cell Transplantation for the Generation of Chimeras [PDF]

Journal of Visualized Experiments, 2010
Medaka is a small egg-laying freshwater fish that allows both genetic and embryological analyses and is one of the three vertebrate model organisms in which genome-wide phenotype-driven mutant screens were carried out (1). Divergence of functional overlap of related genes between medaka and zebrafish allows identification of novel phenotypes that are ...
Sean R, Porazinski, Huijia, Wang, Makoto, Furutani-Seiki   +2 more
openaire   +2 more sources

Virtual reality experience in haemato-oncology patients—technical evaluation (ViREB-TE)

BMC Digital Health
Purpose Virtual reality (VR) is increasingly being used in health care. However, its use as part of therapy during prolonged inpatient treatments is less well established. This study assessed the experience of hemato-oncology inpatients, their caregivers
Rob Boots, Cameron Curley, Ashleigh Scott, Nicole Gavin, Edward Morris, Carley Foster, Matthew Jackson, Sally Collet, Damien Thompson, Nadine Wardell, James Vedelago, Stephen Adam   +11 more
doaj   +1 more source

CD4+ T cells in aged or thymectomized recipients of allogeneic stem cell transplantations

Biological Research, 2015
BACKGROUND: CD4+CD25highFOXP3+ regulatory T (Treg) cells, which include thymus-derived and peripherally induced cells, play a central role in immune regulation, and are therefore crucial to prevent graft-versus-host disease (GVHD).
Hiroshi Takahashi, Kazuhiko Ikeda, Kazuei Ogawa, Syunnichi Saito, Alain M Ngoma, Yumiko Mashimo, Koki Ueda, Miki Furukawa, Akiko Shichishima-Nakamura, Hiroshi Ohkawara, Kenneth E Nollet, Hitoshi Ohto, Yasuchika Takeishi   +12 more
doaj   +1 more source