Results 151 to 160 of about 49,168 (311)

Fludarabine-Based Conditioning Chemotherapy for Allogeneic Hematopoietic Stem Cell Transplantation in Acquired Severe Aplastic Anemia

, 2011
Thirty-eight patients who met the diagnostic criteria for severe aplastic anemia underwent allogeneic hematopoietic stem cell transplantation (HSCT). The median patient age was 20 years (range, 14-36 years).
Walid Rasheed, Elkum, Naser, Fahad Al-Sharif, Naeem Chaudhri, Saleh, Abu Jafar Mohammed, Aljurf, Mahmoud, Fazal Hussain, Said Mohamed, Khalid Ibrahim, Patel, Moosa, Nurgat, Zubeir, Mahmoud Bakr, Hussain, Fazal, Bakr, Mahmoud, Al-Mohareb, Fahad, Al-Zahrani, Hazzaa, Naser Elkum, Al-Anazi, Khalid, Al-Sharif, Fahad, Shad Ahmed, Amr Nassar, Moosa Patel, Hazzaa Al-Zahrani, Fahad Al-Mohareb, Nassar, Amr, Zubeir Nurgat, Rasheed, Walid, Ibrahim, Khalid, Elhassan, Tusneem, Chaudhri, Naeem, Abu Jafar Mohammed Saleh, Tusneem Elhassan, Mahmoud Aljurf, Mohamed, Said, Khalid Al-Anazi, Ahmed, Shad   +35 more
core   +1 more source

Transplant Conditioning [PDF]

, 2020
openaire   +1 more source

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Practical aspects and procedures, including conditioning protocols and haploidentical transplantation

, 2009
Age limits and exclusion criteria for transplantation page 237 Commonly used upper age limits for transplantation 237 Exclusion criteria for transplantation 237 SCT-specific comorbidity index 238 General pretransplant workup 240 Definition of disease ...
Lazarus H.M., Atkinson K., Munker R.
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Hematopoietic Cell Transplantation Using Reduced-Intensity Conditioning Is Successful in Children with Hematologic Cytopenias of Genetic Origin

, 2015
Genetically derived hematologic cytopenias are a rare heterogeneous group of disorders. Allogeneic hematopoietic cell transplantation (HCT) is curative but offset by organ toxicities from the preparative regimen, graft rejection, graft-versus-host ...
Kothari, Alok, Haut, Paul, Loechelt, Brett J., Ngwube, Alexander, Hayashi, Robert, Shenoy, Shalini, Murray, Lisa, Davis, Jeffrey   +7 more
core   +1 more source

Post-transplant cyclophosphamide in haploidentical stem cell transplantation: evaluating the impact of transplant conditioning intensity

Frontiers in Immunology
BackgroundThe introduction of posttransplant cyclophosphamide (PTCy) is one of the major achievements in the field of haploidentical stem cell transplantation (haplo-HCT). The transplant conditioning intensity (TCI) score is a refined classification of conditioning regimens that assigns weight scores to conditioning regimen components.
Pizzano U., Piemontese S., Facchin G., Greco R., Battista M. L., Peccatori J., Fanin R., Ciceri F., Patriarca F., Lupo-Stanghellini M. T.   +9 more
openaire   +3 more sources

Piezoelectric Surface Charge and Dynamic Stimulation Synergize to Promote Cardiac Myoblast Alignment and Maturation

Advanced Healthcare Materials, EarlyView.
Surface polarization of PVDF films combined with mechanical stimulation generates piezoelectric electrical cues that modulate cardiomyoblast behaviour. Non‐poled and poled PVDF substrates provide distinct electroactive microenvironments influencing cell adhesion, proliferation, and differentiation.
Rafaela M Meira, Sylvie Ribeiro, Senentxu Lanceros‐Mendez, Clarisse Ribeiro   +3 more
wiley   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Allogeneic Hematopoietic Cell Transplantation with Full-Intensity Conditioning for Adult Acute Lymphoblastic Leukemia: Results from a Single Center, 1998-2006

, 2011
A retrospective analysis identified 161 consecutive adults with acute lymphoblastic leukemia who underwent allogeneic hematopoietic cell transplantation (HCT) with full-intensity (myeloablative) conditioning between 1998 and 2006.
Gooley, Ted A., Ted A. Gooley, H. Joachim Deeg, Flowers, Mary E.D., Mary E.D. Flowers, Storb, Rainer, Doney, Kristine, Rainer Storb, Kristine Doney, Frederick R. Appelbaum, Deeg, H. Joachim, Appelbaum, Frederick R.   +11 more
core   +1 more source