Results 11 to 20 of about 40,457 (265)

To condition or not to condition—That is the question: The evolution of nonmyeloablative conditions for transplantation [PDF]

open access: yesExperimental Hematology, 2016
In 1985, Eugene Cronkite and his colleagues published, in Experimental Hematology, data indicating that five consecutive "transfusions" of large numbers of marrow cells significantly increase the number of donor-derived cells detected by day 10 of a spleen colony-forming assay, the most primitive hematopoietic cells detectable at that time, present in ...
openaire   +2 more sources

Expanding transplant options to patients over 50 years. Improved outcome after reduced intensity conditioning mismatched-unrelated donor transplantation for patients with acute myeloid leukemia: a report from the Acute Leukemia Working Party of the EBMT

open access: yesHaematologica, 2016
The outcome of patients undergoing HLA-matched unrelated donor allogeneic hematopoietic cell transplantation following reduced-intensity conditioning or myeloablative regimens is reported to be equivalent; however, it is not known if the intensity of the
Bipin N. Savani   +19 more
doaj   +1 more source

CONDITIONS DETERMINING THE TRANSPLANTABILITY OF TISSUES IN THE BRAIN [PDF]

open access: yesJournal of Experimental Medicine, 1923
In confirmation of Shirai's observation, we find that transplantable mouse tumors grow actively when inoculated into the brains of rats, guinea pigs, and pigeons, whereas subcutaneous or intramuscular grafts in the same animals fail. This growth of foreign tissue in the brain, however, takes place only when the grafted material lies entirely in the ...
J B, Murphy, E, Sturm
openaire   +2 more sources

Ischemic Conditioning in Kidney Transplantation

open access: yesJournal of Cardiovascular Pharmacology and Therapeutics, 2017
Ischemia–reperfusion injury is a composite of the injury sustained during a period of reduced or absent blood flow to a tissue or organ and the additional insult sustained on reperfusion, which limits the amount of tissue that can be salvaged. Ischemia–reperfusion injury is the predominant insult during kidney transplantation, contributing to graft ...
Veighey, K, MacAllister, R
openaire   +3 more sources

Role of reduced intensity conditioning in T-cell and B-cell immune reconstitution after HLA-identical bone marrow transplantation in ADA-SCID

open access: yesHaematologica, 2010
The treatment of choice for severe combined immunodeficiency is bone marrow transplantation from an HLA-identical donor sibling without conditioning.
Caterina Cancrini   +9 more
doaj   +1 more source

Difficult Vascular Conditions in Kidney Transplantation

open access: yesTransplantation Proceedings, 2006
The new dialytic and medical therapies have improved the survival of uremic patients and their preservation of a efficacious clinical condition so as to warrant suitability for transplantation, even after a long period of dialysis. In addition, today the use of a "marginal donor" and "marginal kidney" are often used to increase the pool of available ...
P. De Rosa   +6 more
openaire   +5 more sources

Reconstitución inmune exitosa mediante trasplante de células madre hematopoyéticas en un paciente colombiano afectado con enfermedad granulomatosa crónica

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2016
Introducción. La enfermedad granulomatosa crónica es una inmunodeficiencia primaria causada por mutaciones en los genes que codifican para las proteínas del sistema de la oxidasa de NADPH (Nicotinamide Adenine Dinucleotide Phosphate) de las células ...
Yermis Carolina Rocha   +6 more
doaj   +1 more source

Reduced intensity conditioning HLA identical sibling donor allogeneic stem cell transplantation for patients with follicular lymphoma: long-term follow-up from two prospective multicenter trials

open access: yesHaematologica, 2010
Background Allogeneic hematopoietic stem cell transplantation is an effective treatment for patients with poor risk lymphoma, at least in part because of the graft-versus-lymphoma effect. Over the past decade, reduced intensity conditioning regimens have
José Luis Piñana   +13 more
doaj   +1 more source

Peripheral blood stem cell graft compared to bone marrow after reduced intensity conditioning regimens for acute leukemia: a report from the ALWP of the EBMT

open access: yesHaematologica, 2016
Increasing numbers of patients are receiving reduced intensity conditioning regimen allogeneic hematopoietic stem cell transplantation. We hypothesized that the use of bone marrow graft might decrease the risk of graft-versus-host disease compared to ...
Bipin N. Savani   +20 more
doaj   +1 more source

URETERAL TRANSPLANTATION IN INOPERABLE CONDITIONS OF THE BLADDER [PDF]

open access: yesJournal of the American Medical Association, 1919
Perhaps no class of patients makes a more piteous appeal to the surgeon than those with inoperable new growths in any location. And perhaps saddest of all are those patients with growths of the bladder in which the irritation and pain are constant and intense and a resection cannot be made, because either the entire bladder is involved or the area ...
openaire   +2 more sources

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