Results 11 to 20 of about 49,168 (311)

Personalized prediction of overall survival in patients with AML in non‐complete remission undergoing allo‐HCT

Cancer Medicine, 2021
Allogenic hematopoietic stem cell transplantation (allo‐HCT) is the standard treatment for acute myeloid leukemia (AML) in non‐complete remission (non‐CR); however, the prognosis is inconsistent.
Shigeki Hirabayashi, Ryuji Uozumi, Tadakazu Kondo, Yasuyuki Arai, Takahito Kawata, Naoyuki Uchida, Atsushi Marumo, Kazuhiro Ikegame, Takahiro Fukuda, Tetsuya Eto, Masatsugu Tanaka, Atsushi Wake, Junya Kanda, Takafumi Kimura, Ken Tabuchi, Tatsuo Ichinohe, Yoshiko Atsuta, Masamitsu Yanada, Shingo Yano   +18 more
doaj   +1 more source

Thiotepa, Busulfan, Cyclophosphamide: Effective but Toxic Conditioning Regimen Prior to Autologous Hematopoietic Stem Cell Transplantation in Central Nervous System Lymphoma

Medical Sciences, 2023
In primary central nervous system lymphoma, two-year progression-free survival rates of up to 63 percent have been reported for first-line autologous stem cell transplantation after conditioning with the thiotepa busulfan cyclophosphamide regimen ...
Lebon Delphine, Debureaux Pierre-Edouard, Royer Bruno, Gruson Bérengère, Joris Magalie, Votte Patrick, Marolleau Jean-Pierre, Morel Pierre   +7 more
doaj   +1 more source

Phase II Trial of Allogeneic Transplantation Plus Novel Drugs in Multiple Myeloma: Effect of Intensifying Reduced-Intensity Conditioning with Bortezomib and Adding Maintenance Treatment [PDF]

, 2022
The use of reduced-intensity conditioning (RIC) regimens has decreased the risk of nonrelapse mortality (NRM) after allogeneic stem cell transplantation (alloSCT).
European Myeloma Network, the European Society for Blood and Marrow Transplantation, and the Spanish Group of Transplantation, Francesca Patriarca, Reguera, Juan L, Pilar Herrera, Pérez-Simón, José A., Spanish Group of Transplantation, Bruno, Benedetto, Reinoso-Segura, Marta, Benedetto Bruno, Marta Reinoso-Segura, José A. Pérez-Simón, García-Cadenas, Irene, Gösta Gahrton, Fanin, Renato, Caballero-Velázquez, Teresa, Garcia Cadenas, Irene, Miquel Granell, Teresa Caballero-Velázquez, Nahi, Hareth, Hareth Nahi, Reguera-Ortega, Juan Luis, Granell, Miquel, López-Corral, Lucía, European Myeloma Network, Renato Fanin, Juan L. Reguera, Herrera, Pilar, Gahrton, Gösta, Hermann Einsele, Pérez-Simón, José A, Lucía López-Corral, Caballero Velazquez, Teresa, Reguera, Juan L., Irene García-Cadenas, European Society for Blood and Marrow Transplantation, Universitat Autònoma de Barcelona, Patriarca, Francesca, Einsele, Hermann   +37 more
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A comparison between low intensity and reduced intensity conditioning in allogeneic hematopoietic stem cell transplantation for solid tumors

Haematologica, 2008
Background Following different types of conditioning, allogeneic hematopoietic stem cell transplantation produces a graft-versus-tumor effect in patients with solid tumors.
Réka Conrad, Mats Remberger, Kerstin Cederlund, Olle Ringdén, Lisbeth Barkholt   +4 more
doaj   +1 more source

CONDITIONS DETERMINING THE TRANSPLANTABILITY OF TISSUES IN THE BRAIN [PDF]

Journal of Experimental Medicine, 1923
In confirmation of Shirai's observation, we find that transplantable mouse tumors grow actively when inoculated into the brains of rats, guinea pigs, and pigeons, whereas subcutaneous or intramuscular grafts in the same animals fail. This growth of foreign tissue in the brain, however, takes place only when the grafted material lies entirely in the ...
J B, Murphy, E, Sturm
openaire   +2 more sources

Lasting Gammaproteobacteria profile changes characterized hematological cancer patients who developed oral mucositis following conditioning therapy

Journal of Oral Microbiology, 2020
Background Oral mucositis (OM) is a common side effect of conditioning therapy implemented before hematopoietic stem cell transplantation (HSCT). The role of oral microbiome in OM is not fully elucidated.
Jean-Luc C. Mougeot, Micaela F. Beckman, Craig B. Stevens, Kathryn G. Almon, Darla S. Morton, Inger Von Bültzingslöwen, Michael T. Brennan, Farah Bahrani Mougeot   +7 more
doaj   +1 more source

To condition or not to condition—That is the question: The evolution of nonmyeloablative conditions for transplantation [PDF]

Experimental Hematology, 2016
In 1985, Eugene Cronkite and his colleagues published, in Experimental Hematology, data indicating that five consecutive "transfusions" of large numbers of marrow cells significantly increase the number of donor-derived cells detected by day 10 of a spleen colony-forming assay, the most primitive hematopoietic cells detectable at that time, present in ...
openaire   +2 more sources

Regulatory immune cells in transplantation. [PDF]

, 2012
Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control both the innate immune response triggered by the injured ...
Bushell, Andrew, Wood, Kathryn, Bushell, A, Hester, J, Wood, Kathryn J, Andrew Bushell, Joanna Hester, Kathryn J. Wood, Wood, KJ, Hester, Joanna   +9 more
core   +1 more source

Expanding transplant options to patients over 50 years. Improved outcome after reduced intensity conditioning mismatched-unrelated donor transplantation for patients with acute myeloid leukemia: a report from the Acute Leukemia Working Party of the EBMT

Haematologica, 2016
The outcome of patients undergoing HLA-matched unrelated donor allogeneic hematopoietic cell transplantation following reduced-intensity conditioning or myeloablative regimens is reported to be equivalent; however, it is not known if the intensity of the
Bipin N. Savani, Myriam Labopin, Nicolaus Kröger, Jürgen Finke, Gerhard Ehninger, Dietger Niederwieser, Rainer Schwerdtfeger, Donald Bunjes, Bertram Glass, Gerard Socié, Per Ljungman, Charles Craddock, Frédéric Baron, Fabio Ciceri, Norbert Claude Gorin, Jordi Esteve, Christoph Schmid, Sebastian Giebel, Mohamad Mohty, Arnon Nagler   +19 more
doaj   +1 more source

Quantitative and qualitative differences in use and trends of hematopoietic stem cell transplantation:a Global Observational Study [PDF]

, 2013
Fifty-five years after publication of the first hematopoietic stem cell transplantation this technique has become an accepted treatment option for defined hematologic and non-hematologic disorders.
Madrigal, Alejandro, Horowitz, Mary, Passweg, Jakob, Bouzas, Luis Fernando, Szer, Jeff, Niederwieser, Dietger, Gratwohl, Alois, Aljurf, Mahmoud, Iida, Minako, Kodera, Yoshihisa, Worldwide Network Blood Marrow Tra, Pasquini, Marcelo C., Marrow Transplantation,, Lipton, Jeff, Worldwide Network of Blood,, Gratwohl, Michael, Baldomero, Helen, Frauendorfer, Karl   +17 more
core   +1 more source