Results 201 to 210 of about 40,457 (265)

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Opinion: a call for safe therapeutic and gastric interventions for adolescents and young adults with obesity and transplant-indicated leukemia. [PDF]

Front Oncol
Garcia MB, Perales P, Santos D, Tzeng CD, Cuglievan B, Sheikh IN.   +5 more
europepmc   +1 more source

SSR4 sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

Advanced Science, EarlyView.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao, Youcai Zhao, Haiyang Li, Bowen Yang, Siyan Lu, Xueting Fu, Caixia Zhang, Yirong Chen, Xiaofeng Bian, Xinghua Ma, Xiaobing Yang, Bin Wang, Yuan Fang, Lulu Yang, Yelin Zhao, Shuli Zhao   +15 more
wiley   +1 more source

Refining busulfan exposure enhances pediatric ALL HSCT outcomes: insights from the International FORUM study. [PDF]

Blood Adv
Ben Hassine K, Gloor Y, Dupanloup I, Uppugunduri CRS, Mlakar V, Gonzales F, Güngör T, Ifversen M, Shaw PJ, Buechner J, Truong TH, Bittencourt H, Teague L, Toporski J, Sedlacek P, Poetschger U, Krajinovic M, Kałwak K, Balduzzi A, Algeri M, Bader P, Peters C, Dalle JH, Ansari M.   +23 more
europepmc   +1 more source

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

Superior long-term survival with acceptable safety of ATG/G-CSF-based haplo-HSCT with intensified BU+MEL/TT conditioning in CR Pediatric Non-DS-AMKL. [PDF]

Front Oncol
Pan F, Long J, Cao XY, Lu Y, Zhang JP, Zhao YL, Xiong M, Pan FM, Yue GL, Gao K, Wei ZJ.   +10 more
europepmc   +1 more source

Navigating Haploidentical Stem Cell Transplantation in Congenital Amegakaryocytic Thrombocytopenia With Prior Intracranial Bleeding: Report of Two Pediatric Cases. [PDF]

Cureus
Tulsiyan A, Radhakrishnan N, Singh A, Bhattacharya S, Gaire H, Arora S, Dua S, Singh S, Srivastava A.   +8 more
europepmc   +1 more source

Serum Syndecan-1: a potent prognostic biomarker for transplant outcomes. [PDF]

Front Med (Lausanne)
Yokokawa T, Fukatsu M, Fukuchi K, Sato Y, Sano T, Koyama D, Kimura S, Furukawa M, Yamada S, Ikezoe T.   +9 more
europepmc   +1 more source

Nutritional Impact of High-Dose Melphalan in Autologous Stem Cell Transplantation. [PDF]

Cureus
El Ouafa Y, Fadi M, Benrahma H, Bouanani N.   +3 more
europepmc   +1 more source

CRP patterns and clinical associations in febrile patients undergoing autologous bone marrow transplant: experience from the sole transplant center in the West Bank, Palestine. [PDF]

Ann Hematol
Ghoul I, Battat M, Khursani A, Amer R, Wild-Ali M, Muslm S, Shawahna R, Hayek M.   +7 more
europepmc   +1 more source