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Murine Models of Bone-Marrow Transplant Conditioning
2002Hematopoietic stem-cell transplantation (SCT) is a rapidly evolving clinical strategy for treating a variety of malignancies or disorders of the lymphohematopoietic system. Bone-marrow cells or, more recently, mobilized peripheral blood (MPB) stem cells, are used as a vital source of hematopoietic cells that can reconstitute the host and rescue the ...
van Os, Ronald, Down, Julian
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Novel approaches to transplant conditioning
Hematological Oncology, 2001Hennessy, B.J. +2 more
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Changing Approaches to Transplant Conditioning for Hematologic Malignancy
Journal of Hematotherapy, 1999H E C L A SS IC C O N C E P T R E G A R D IN G BMT in hematologic malignancy holds that myeloablative conditioning is a prerequisite for cure. However, as many as one third of patients may die from complications after this procedure. A preliminary publication in 1985, dealing with 5 cases of accelerated CML using dibromomannitol/ cytarabine ...
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Conditioning regimens for allogeneic stem cell transplants
Current Opinion in Hematology, 2000In addition to providing cytoreduction at myeloablative dose intensity, conditioning regimens for allogeneic transplantation are designed to immunosuppress the recipient to permit donor lymphohematopoietic engraftment and thereby establish a graft-versus-malignancy effect.
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Optimal Conditions of Transplantable Binary Polyelectrolyte Microcapsules
Annals of the New York Academy of Sciences, 2001Abstract: Binary polyanion/oligocation microcapsules, prepared in a one‐step process, are proposed as an alternative to the common alginate/poly‐l‐lysine system used in bioencapsulation technology. The model system is based on natural polysaccharides and involves the anionic sodium alginate, or iota‐carrageenan, complexed with cationic oligochitosan ...
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Graft Condition and Mortality in Heart Transplantation
2015G. Dureau +21 more
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