Results 61 to 70 of about 538,193 (321)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Quantitative Phase Imaging Camera With a Weak Diffuser

Frontiers in Physics, 2019
We introduce the quantitative phase imaging camera with a weak diffuser (QPICWD) as an effective scheme of quantitative phase imaging (QPI) based on normal microscope platforms.
Linpeng Lu, Linpeng Lu, Linpeng Lu, Jiasong Sun, Jiasong Sun, Jiasong Sun, Jialin Zhang, Jialin Zhang, Jialin Zhang, Yao Fan, Yao Fan, Yao Fan, Qian Chen, Qian Chen, Chao Zuo, Chao Zuo, Chao Zuo   +16 more
doaj   +1 more source

Algal Concentration Dynamical Model Simulation in Sewon, Bantul, Yogyakarta Facultative Wastewater Treatment Pond [PDF]

E3S Web of Conferences, 2019
In this paper, we simulate a dynamical model of the algal concentration transport by using data collected in Sewon, Bantul, Yogyakarta facultative wastewater treatment ponds to analyse and evaluate the dynamic of the algal concentration.
Sunarsih, Widowati, Kartono, Sutrisno
doaj   +1 more source

Radiative transfer of acoustic waves in continuous complex media: Beyond the Helmholtz equation [PDF]

, 2016
Heterogeneity can be accounted for by a random potential in the wave equation. For acoustic waves in a fluid with fluctuations of both density and compressibility (as well as for electromagnetic waves in a medium with fluctuation of both permittivity and
Baresch, Diego, Baydoun, Ibrahim, Derode, Arnaud, Pierrat, Romain   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Effects of Rainfall Intensity, Kinetic Energy and Slope Angle to the Upslope, Downslope, and Lateral Slope Components of Splash Erosion in Hillslope Agriculture: A Case in Badiangan, Ajuy, Iloilo [PDF]

Nature Environment and Pollution Technology
This study was conducted in Barangay Badiangan, Ajuy, Iloilo City, Philippines (11°10’N, 122°58’E) to determine the effects of rainfall intensity and other rainfall-derived parameters on the directional components of splash erosion in hillslopes.
Shevanee Ruth G. dela Cruz and Ricardo L. Fornis
doaj   +1 more source

Advances in Phase Retrieval by Transport of Intensity Equation

Proceedings of the 7th International Conference on Photonics, Optics and Laser Technology, 2019
There are many factors in the calculations of Transport of Intensity Equation, which may lead to the uncertainty of the retrieved phase. In this paper, effect of these parameters such as defocus distance, focus plane and magnification, on the results is studied. It is hoped that this would provide a more robust and reliable method for phase and optical
Yingjie Yu, Chi Wang, Chongtian Huang, Liansheng Sui, Anand Asundi, Dingfu Chen   +5 more
openaire   +1 more source

Fluctuation-driven directed transport in the presence of Levy flights

, 2007
Numerical evidence of directed transport driven by symmetric Levy noise in time-independent ratchet potentials in the absence of an external tilting force is presented.
A.V. Chechkin, Bouchaud, Brockmann, Brockmann, Brockmann, Buldyrev, Buldyrev, Carati, Chechkin, Chechkin, Chechkin, Chechkin, Chechkin, Chechkin, Chechkin, D. del-Castillo-Negrete, del-Castillo-Negrete, del-Castillo-Negrete, del-Castillo-Negrete, del-Castillo-Negrete, Ditlevsen, Ditlevsen, Ditlevsen, Dubkov, Dubkov, Dybiec, Dybiec, Feynman, Gnedenko, Gonchar, Imkeller, Jespersen, Jha, Kassam, Katori, Klafter, Levandowsky, Lomholt, Lévy, Mandelbrot, Mantegna, Mateos, Metzler, Nikias, Patriarca, Peng, Phillips, Podlubny, Reimann, Rosa, Samorodnitsky, Samorodnitsky, Samorodnitsky, Segev, Shlesinger, Solomon, V.Yu. Gonchar, Viswanathan, Vlad, Wegman   +59 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source