Results 181 to 190 of about 3,354,548 (316)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Metabolomic insights into inter-familial and pre-transport treatment effects on live transport stress in selectively-bred mussels, Perna canaliculus. [PDF]
MetabolomicsCheng MCF +5 more
europepmc +1 more source
Seamless Transport: Case Study Compendium
, 2012 Member Countries of the International Transport Forum and International Organisations working in the field of transport were asked to submit examples of good practice in seamless transport as an input to Summit 2012. Fifty case studies were received from
International Transport Forum
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Transport planning education in urban planning schools in Australia
, 2013 In the next four decades, seventy per cent of the world's population will become urban, demanding improved mobility and better accessibility. Yet current transport planning practice at both international and domestic level has not been able to keep pace ...
Burke, MI, Mateo-Babiano, I
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Adverse events and clinical risk factors during intrahospital transport of critically ill neonates: a prospective pilot study at a tertiary center in Vietnam. [PDF]
Front PediatrBinh HTT +3 more
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Comparative boundary-layer analysis of Buongiorno nanofluid flow over flat surfaces: Blasius, Sakiadis, stagnation-point, and stretching-sheet configurations. [PDF]
Discov NanoFaisal M +3 more
europepmc +1 more source
Social exclusion and transport policy
, 2004 This paper is a review of social inclusion in the specification by central government of policy instruments for local government. It forms part of the scooping study on Accessibility and User Needs in Transport (AUNT) funded by the EPSRC Sustainable ...
Titheridge, H.
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