Results 191 to 200 of about 5,329 (286)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Transit Competitiveness in Polycentric Metropolitan Regions

, 2007
This paper analyzes the potential to, and impacts of, increasing transit modal split in a polycentric metropolitan area – the Philadelphia, Pennsylvania region.
Casello, Jeffrey M
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Improving Transit Integration Among Multiple Providers, Volume I: Transit Integration Manual

, 2015
TCRP Report 173: Improving Transit Integration Among Multiple Providers presents a comprehensive set of guidelines and procedures to assist transit agencies in evaluating, planning, and implementing steps to integrate transit services in areas with ...
Goldman, Joey, Murray, Gail, Whitaker, Bethany, Sullivan, Cathleen, Whelan, Nancy, Spencer, Tina, Chase, Mark, Reisman, Alexandra   +7 more
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

ECONOMIC IMPACT OF INTERNATIONAL TRANSPORT CORRIDORS ON UZBEKISTAN'S TRADE AND TRANSIT POTENTIAL

Maaz Ahmad, Narzullayev Bekhruz
openalex   +2 more sources

Land-Use Transport Interaction: State of the Art [PDF]

This paper investigates innovative approaches to the integration of land-use and transport planning in urban regions. Engineering, economic and social-science based theories and empirical studies are analyzed regarding their ability to explain the ...
Michael Wegener, Franz Fuerst
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Potential Impacts of Federal Health Care Reform on Public Transit

, 2013
In March 2010, President Obama signed into law the most dramatic overhaul of the American health care system since the creation of Medicare in 1965.
Whitaker, Bethany, Oettinger, Ellen, Santalucia, Antonio   +2 more
core  

23: Gendered mobilities, transport norms and the potential for sustainable climate transitions

Published
Kronsell, Annica, Stepanova, Olga, Dymén, Christian, Hiselius, Lena Winslott, Rosqvist, Lena Smidfelt   +4 more
openaire   +1 more source