Results 171 to 180 of about 5,329 (286)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

E-Purse Transit Pass: The Potential of Public Transport Smart Card System in the Philippines

, 2018
Desiree I. Cendana, Neriza V. Bustillo, Thelma D. Palaoag   +2 more
openalex   +2 more sources

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Simulating Impacts from Transit Service Enhancements in the San Francisco Bay Area

Preemptively assessing the potential impacts of large transportation projects is an essential step in achieving better outcomes. However, for transformative public transit projects, it can be difficult to weigh the many complicated downstream impacts on ...
Waraich, Rashid, Laarabi, Haitam, Guirado, Carlos, Todd-Blick, Annika, Fujita, K. Sydny, Poliziani, Cristian, Spurlock, C. Anna, Rezaei, Nazanin, Wenzel, Tom, Needell, A. Zachary, Caicedo, D. Juan   +10 more
core   +1 more source

Analyzing potential transport mode shifting behavior from car to Bus Rapid Transit (BRT) in Nairobi, Kenya [PDF]

, 2018
A. Grigolon, P. Lumumba, M. Brussel
openalex  

Development of transit potential in conditions of integration of the Republic of Kazakhstan into International transport system

, 2018
Tynys Suleimenov, T. T. Sultanov, Gulnar Tlepiyeva   +2 more
openalex   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Ukraine’s Transit Potential Amid the Russian Invasion and European Integration

Lex Portus
The article outlines the dynamics of Ukraine’s transit routes through the European Union and the Republic of Moldova and their institutional development in 2022-2023 amid the Russo-Ukrainian armed conflict.
Volodymyr Nikiforenko, Yurii Kuryliuk
doaj   +1 more source